Detailed description page of Selected OV_ID


OV_1146 details
Primary information
OV_IDOV_1146
Virus Name Herpes simplex virus
StrainMutant
Virus typeDNA
Virus familyHerpesviridae
Modification in virus genomeMutant for gamma 34.5, lacZ and alpha 47 gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismBALB/c nude mice xenograft for Human prostatic cancer HONDA
In-vivo virus concentration2 × 10⁶ pfu
In-vivo toxicityNA
In-vivo resultTotal reduction in tumor volume in 2 mice after 3 days
Mode of deliveryIntraneoplastically
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID16278413