Detailed description page of Selected OV_ID


OV_1136 details
Primary information
OV_IDOV_1136
Virus Name Sindbis virus
StrainAR339
Virus typeRNA
Virus familyTogaviridae
Modification in virus genomeNone
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismBALB/c nude mice xenograft for HeLaS3 cell line
In-vivo virus concentration1 × 10⁶ pfu
In-vivo toxicityNA
In-vivo resultComplete reduction in tumor volume after 30 days
Mode of deliveryIntratumoral injection
Pathway inductionApoptosis induction in cancer cell lines
Immunogenic effectNA
Clinical trial
PMID15958641