Detailed description page of Selected OV_ID


OV_1092 details
Primary information
OV_IDOV_1092
Virus Name Herpes simplex virus
StrainHSV-1
Virus typeDNA
Virus familyHerpesviridae
Modification in virus genomeMutant NV1066
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineMediGene Inc. San Diego, CA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismNude mice xenograft for CHLA-20
In-vivo virus concentration1 × 10⁷ pfu of NV1066" NA significant reduction in tumor size, shows 87.5 response rate Intratumoral injection Apoptosis induction and cspase 3 activation NA NA 15570577 OV_1093 Herpes simplex virus HSV-1 DNA Herpesviridae Mutant NV1066 Yes No No Med
In-vivo toxicity
In-vivo result
Mode of delivery
Pathway induction
Immunogenic effect
Clinical trial
PMID