Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 7. Click on ID to see further detail.
IDOV_3167Virus nameSemliki forest virusVirus strainSFV-VA7Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman prostate cancer cell lineCell lineVCaPConcentration of cell line40000 cells per wellIn-vitro toxicityNAAssayCell proliferation kit 1 assayIn-vitro virus concentration0.01 MOIIn-vitro result100% cell deathModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID28557974
IDOV_3168Virus nameSemliki forest virusVirus strainSFV-VA7Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman prostate cancer cell lineCell lineVCaPConcentration of cell line40000 cells per wellIn-vitro toxicityNAAssayCell proliferation kit 1 assayIn-vitro virus concentration0.1 MOIIn-vitro result100% cell deathModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID28557974
IDOV_3169Virus nameSemliki forest virusVirus strainSFV-VA7Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman prostate cancer cell lineCell lineVCaPConcentration of cell line40000 cells per wellIn-vitro toxicityNAAssayCell proliferation kit 1 assayIn-vitro virus concentration1 MOIIn-vitro result100% cell deathModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID28557974
IDOV_3170Virus nameSemliki forest virusVirus strainSFV-VA7Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman prostate cancer cell lineCell lineVCaPConcentration of cell line40000 cells per wellIn-vitro toxicityNAAssayCell proliferation kit 1 assayIn-vitro virus concentration10 MOIIn-vitro result100% cell deathModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID28557974
IDOV_3727Virus nameVesicular stomatitis virusVirus strainVSV-GPVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationvirus expressing GP proteinVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman prostate cancer cell lineCell lineVCaPConcentration of cell lineNAIn-vitro toxicityNAAssayAbsorbance measurementsIn-vitro virus concentration0.1 MOIIn-vitro result70% cell viableModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryVirus induce apoptosis in cancer cellPathway inducedNAImmunogenic effectNAClinical trialNAPMID29696636
IDOV_3734Virus nameVesicular stomatitis virusVirus strainVSV-GPVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationvirus expressing GP proteinVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman prostate cancer cell lineCell lineVCaPConcentration of cell lineNAIn-vitro toxicityNAAssayAbsorbance measurementsIn-vitro virus concentration10 MOIIn-vitro result30% cell viableModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryVirus induce apoptosis in cancer cellPathway inducedNAImmunogenic effectNAClinical trialNAPMID29696636
IDOV_3740Virus nameVesicular stomatitis virusVirus strainVSV-GPVirus genome typeRNAVirus familyRhabdoviridaeVirus genome modificationvirus expressing GP proteinVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman prostate cancer cell lineCell lineVCaPConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismBalb/c-rag and gamma negative xenograft for VCap (2.0E+6)In-vivo virus concentration1.0E+7 pfuIn-vivo toxicityNA In-vivo resultRegression in tumor volume to 0.3 cm after day 80Mode of deliveryIntratumoralPathway inducedNAImmunogenic effectNAClinical trialNAPMID29696636