The total number of records retrieved from this search are 4. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
IDOV_3518	Virus nameAdenovirus	Virus strainAdenovirus ZD55-shMYCN	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationVirus expressing MYCN gene	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineLab own synthesized	Origin of cell lineHuman neuroblastoma cell line	Cell lineLA1-55n/Dox-R	Concentration of cell line2.0E+5 cells per well	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration10 MOI	In-vitro result50% cells remain viable after 6 days	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis as measured by TUNEL assay	Immunogenic effectNA	Clinical trialNA	PMID28711493
IDOV_3519	Virus nameAdenovirus	Virus strainAdenovirus ZD55-shMYCN	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationVirus expressing MYCN gene	Virus aloneNo	Virus in combination with drug/radiationVirus in combination with doxorubicin	Immune gene insertion in viral genomeNo	Source of cell lineLab own synthesized	Origin of cell lineHuman neuroblastoma cell line	Cell lineLA1-55n/Dox-R	Concentration of cell line2.0E+5 cells per well	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration10 MOI	In-vitro result2% cells remain viable after 6 days	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis as measured by TUNEL assay	Immunogenic effectNA	Clinical trialNA	PMID28711493
IDOV_3520	Virus nameAdenovirus	Virus strainAdenovirus ZD55-shMYCN	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationVirus expressing MYCN gene	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineLab own synthesized	Origin of cell lineHuman neuroblastoma cell line	Cell lineLA1-55n/Dox-R	Concentration of cell lineNA	In-vitro toxicityNA	AssayNA	In-vitro virus concentrationNA	In-vitro resultNA	Model organismBalb/c nude mice xenograft for LA1-55n/Dox-R cell line (2.0E+6)	In-vivo virus concentration7.0E+8 pfu	In-vivo toxicityNA	In-vivo resultTumor volume regressed to 800mm after four week compared to normal 1400 mm.	Mode of deliveryNA	Pathway inducedInduction of apoptosis as measured by TUNEL assay	Immunogenic effectNA	Clinical trialNA	PMID28711493
IDOV_3521	Virus nameAdenovirus	Virus strainAdenovirus ZD55-shMYCN	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationVirus expressing MYCN gene	Virus aloneNo	Virus in combination with drug/radiationVirus in combination with Doxorubicin	Immune gene insertion in viral genomeNo	Source of cell lineLab own synthesized	Origin of cell lineHuman neuroblastoma cell line	Cell lineLA1-55n/Dox-R	Concentration of cell lineNA	In-vitro toxicityNA	AssayNA	In-vitro virus concentrationNA	In-vitro resultNA	Model organismBalb/c nude mice xenograft for LA1-55n/Dox-R cell line (2.0E+6)	In-vivo virus concentration7.0E+8 pfu	In-vivo toxicityNA	In-vivo resultTumor volume regressed to 300mm after four week compared to normal 1400 mm.	Mode of deliveryNA	Pathway inducedInduction of apoptosis as measured by TUNEL assay	Immunogenic effectNA	Clinical trialNA	PMID28711493