Browse By Cancer Type Result Page of OvirusTdb

The total number of records retrieved from this search are 8. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_3069Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman stomach cancer cell lineHs746T3.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI18% cell viabilityNoNoNA No responseNANANANA31011628
OV_3070Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman stomach cancer cell lineHs746T3.0E+5 cells per wellNATrypan blue assay10⁻³ MOI1% cell viabilityNoNoNA No responseNANANANA31011628
OV_3071Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1YesNoNoATCCHuman stomach cancer cell lineHs746T3.0E+5 cells per wellNATrypan blue assay10⁻² MOI100% cell deathNoNoNA No responseNANANANA31011628
OV_3099Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman stomach cancer cell lineHs746T3.0E+5 cells per wellNATrypan blue assay10⁻⁴ MOI18% cell viabilityNoNoNA No responseNANANANA31011628
OV_3100Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman stomach cancer cell lineHs746T3.0E+5 cells per wellNATrypan blue assay10⁻³ MOI2% cell viabilityNoNoNA No responseNANANANA31011628
OV_3101Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1YesNoNoATCCHuman stomach cancer cell lineHs746T3.0E+5 cells per wellNATrypan blue assay10⁻² MOI100% cell deathNoNoNA No responseNANANANA31011628
OV_3113Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoATCCHuman stomach cancer cell lineHs746TNANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 3500 mm after 50 daysIntravenousNANANA31011628
OV_3114Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoATCCHuman stomach cancer cell lineHs746TNANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 1000 mm after 50 daysIntravenousNANANA31011628