The total number of records retrieved from this search are 25. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_3060	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	Yes	No	No	ATCC	Human bladder cancer cell line	SW780	3.0E+5 cells per well	NA	Trypan blue assay	10⁻⁴ MOI	50% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3061	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	Yes	No	No	ATCC	Human bladder cancer cell line	SW780	3.0E+5 cells per well	NA	Trypan blue assay	10⁻³ MOI	10% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3062	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	Yes	No	No	ATCC	Human bladder cancer cell line	SW780	3.0E+5 cells per well	NA	Trypan blue assay	10⁻² MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3090	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	Yes	No	No	ATCC	Human bladder cancer cell line	SW780	3.0E+5 cells per well	NA	Trypan blue assay	10⁻⁴ MOI	45% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3091	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	Yes	No	No	ATCC	Human bladder cancer cell line	SW780	3.0E+5 cells per well	NA	Trypan blue assay	10⁻³ MOI	15% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3092	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	Yes	No	No	ATCC	Human bladder cancer cell line	SW780	3.0E+5 cells per well	NA	Trypan blue assay	10⁻² MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3109	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	No	Virus strain in combination with 5-FC (200mg/kg)	No	ATCC	Human bladder cancer cell line	SW780	NA	NA	NA	NA	NA	BD62 mice xenograft for Lovo cell line	1.0E+7 pfu	NA	Tumor volume decreases to below 100 mm after 50 days	Intravenous	NA	NA	NA	31011628
OV_3110	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	No	Virus strain in combination with 5-FC (200mg/kg)	No	ATCC	Human bladder cancer cell line	SW780	NA	NA	NA	NA	NA	BD62 mice xenograft for Lovo cell line	1.0E+7 pfu	NA	Tumor volume decreases to below 100 mm after 50 days	Intravenous	NA	NA	NA	31011628
OV_4278	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human bladder squamous cell carcinoma cell line	SCaBER	4000 cells per well	NA	MTT assay	10 pfu	11.5 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4280	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human bladder transitional cell carcinoma	T24	4000 cells per well	NA	MTT assay	10 pfu	21.1 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4289	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human bladder transitional cell carcinoma	UM-UC-3	4000 cells per well	NA	MTT assay	10 pfu	39.8 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4298	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human bladder carcinoma	5637	4000 cells per well	NA	MTT assay	10 pfu	50.2 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4325	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	SICB	Human bladder transitional cell carcinoma	EJ	4000 cells per well	NA	MTT assay	10 pfu	95.3 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4327	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human bladder transitional cell carcinoma	J82	4000 cells per well	NA	MTT assay	10 pfu	96.8 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4333	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human urinary bladder cancer cell line	T24	4000 cells per well	NA	MTT assay	0.001 MOI	90% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4334	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human urinary bladder cancer cell line	T24	4000 cells per well	NA	MTT assay	0.01 MOI	80% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4335	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human urinary bladder cancer cell line	T24	4000 cells per well	NA	MTT assay	0.1 MOI	50% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4336	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human urinary bladder cancer cell line	T24	4000 cells per well	NA	MTT assay	10 MOI	38% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4337	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human urinary bladder cancer cell line	T24	4000 cells per well	NA	MTT assay	100 MOI	30% cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_5617	Newcastle disease virus	NDV-MK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human bladder carcinoma	HT1197	80% confluency	NA	MTT assay	3 pfu	50% of cancer cell death occurs	No	No	NA	No response	NA	Induction of apoptosis by virus infection	Induction of IFN-Gamma production	NA	US7470426
OV_5618	Newcastle disease virus	NDV-MK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human bladder carcinoma	UM-UC-3	80% confluency	NA	MTT assay	54 pfu	50% of cancer cell death occurs	No	No	NA	No response	NA	Induction of apoptosis by virus infection	Induction of IFN-Gamma production	NA	US7470426
OV_5619	Newcastle disease virus	NDV-MK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human bladder carcinoma	HT1367	80% confluency	NA	MTT assay	422 pfu	50% of cancer cell death occurs	No	No	NA	No response	NA	Induction of apoptosis by virus infection	Induction of IFN-Gamma production	NA	US7470426
OV_5837	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human bladder carcinoma cell line	HT1197	80% confluency	NA	NA	3 pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578
OV_5838	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human bladder carcinoma cell line	UM-UC-3	80% confluency	NA	NA	54 pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578
OV_5839	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human bladder carcinoma cell line	HT1376	80% confluency	NA	NA	422 pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578