Browse By Cancer Type Result Page of OvirusTdb

The total number of records retrieved from this search are 100. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_4834Maraba viruswild typeRNARhabdoviridaeNoneYesNoNoNAHuman ovarian cancer cell lineHEYA850000 cells per wellNACell titer Glo luminiscent assay10 MOI60% cell viability after 24 hoursNoNoNA No responseNANANANA27119108
OV_4835Myxoma viruswild typeDNAPoxviridaeNoneYesNoNoNAHuman ovarian cancer cell lineHEYA850000 cells per wellNACell titer Glo luminiscent assay10 MOI100% cell viability after 48 hoursNoNoNA No responseNANANANA27119108
OV_4836Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoNAHuman ovarian cancer cell lineHEYA850000 cells per wellNACell titer Glo luminiscent assay10 MOI80% cell viability after 48 hoursNoNoNA No responseNANANANA27119108
OV_4837Maraba viruswild typeRNARhabdoviridaeNoneYesNoNoNAHuman ovarian cancer cell lineHEYA850000 cells per wellNACell titer Glo luminiscent assay10 MOI10% cell viability after 48 hoursNoNoNA No responseNANANANA27119108
OV_4838Myxoma viruswild typeDNAPoxviridaeNoneYesNoNoNAHuman ovarian cancer cell lineHEYA850000 cells per wellNACell titer Glo luminiscent assay10 MOI100% cell viability after 72 hoursNoNoNA No responseNANANANA27119108
OV_4839Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoNAHuman ovarian cancer cell lineHEYA850000 cells per wellNACell titer Glo luminiscent assay10 MOI70% cell viability after 72 hoursNoNoNA No responseNANANANA27119108
OV_4840Maraba viruswild typeRNARhabdoviridaeNoneYesNoNoNAHuman ovarian cancer cell lineHEYA850000 cells per wellNACell titer Glo luminiscent assay10 MOI5% cell viability after 72 hoursNoNoNA No responseNANANANA27119108
OV_4841Myxoma viruswild typeDNAPoxviridaeNoneYesNoNoNAHuman ovarian cancer cell lineHEYA850000 cells per wellNACell titer Glo luminiscent assay10 MOI90% cell viability after 4 daysNoNoNA No responseNANANANA27119108
OV_4842Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoNAHuman ovarian cancer cell lineHEYA850000 cells per wellNACell titer Glo luminiscent assay10 MOI50% cell viability after 4 daysNoNoNA No responseNANANANA27119108
OV_4843Maraba viruswild typeRNARhabdoviridaeNoneYesNoNoNAHuman ovarian cancer cell lineHEYA850000 cells per wellNACell titer Glo luminiscent assay10 MOI1% cell viability after 4 daysNoNoNA No responseNANANANA27119108
OV_4844Myxoma viruswild typeDNAPoxviridaeNoneYesNoNoNAHuman ovarian cancer cell lineHEYA850000 cells per wellNACell titer Glo luminiscent assay10 MOI70% cell viability after 5 daysNoNoNA No responseNANANANA27119108
OV_4845Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoNAHuman ovarian cancer cell lineHEYA850000 cells per wellNACell titer Glo luminiscent assay10 MOI20% cell viability after 5 daysNoNoNA No responseNANANANA27119108
OV_4846Maraba viruswild typeRNARhabdoviridaeNoneYesNoNoNAHuman ovarian cancer cell lineHEYA850000 cells per wellNACell titer Glo luminiscent assay10 MOI1% cell viability after 5 daysNoNoNA No responseNANANANA27119108
OV_4847Myxoma viruswild typeDNAPoxviridaeNoneYesNoNoNAHuman ovarian cancer cell lineSKOV350000 cells per wellNACell titer Glo luminiscent assay10 MOI100% cell viability after 24 hoursNoNoNA No responseNANANANA27119108
OV_4848Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoNAHuman ovarian cancer cell lineSKOV350000 cells per wellNACell titer Glo luminiscent assay10 MOI100% cell viability after 24 hoursNoNoNA No responseNANANANA27119108
OV_4849Maraba viruswild typeRNARhabdoviridaeNoneYesNoNoNAHuman ovarian cancer cell lineSKOV350000 cells per wellNACell titer Glo luminiscent assay10 MOI80% cell viability after 24 hoursNoNoNA No responseNANANANA27119108
OV_4850Myxoma viruswild typeDNAPoxviridaeNoneYesNoNoNAHuman ovarian cancer cell lineSKOV350000 cells per wellNACell titer Glo luminiscent assay10 MOI100% cell viability after 48 hoursNoNoNA No responseNANANANA27119108
OV_4851Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoNAHuman ovarian cancer cell lineSKOV350000 cells per wellNACell titer Glo luminiscent assay10 MOI100% cell viability after 48 hoursNoNoNA No responseNANANANA27119108
OV_4852Maraba viruswild typeRNARhabdoviridaeNoneYesNoNoNAHuman ovarian cancer cell lineSKOV350000 cells per wellNACell titer Glo luminiscent assay10 MOI40% cell viability after 48 hoursNoNoNA No responseNANANANA27119108
OV_4853Myxoma viruswild typeDNAPoxviridaeNoneYesNoNoNAHuman ovarian cancer cell lineSKOV350000 cells per wellNACell titer Glo luminiscent assay10 MOI100% cell viability after 72 hoursNoNoNA No responseNANANANA27119108
OV_4854Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoNAHuman ovarian cancer cell lineSKOV350000 cells per wellNACell titer Glo luminiscent assay10 MOI90% cell viability after 72 hoursNoNoNA No responseNANANANA27119108
OV_4855Maraba viruswild typeRNARhabdoviridaeNoneYesNoNoNAHuman ovarian cancer cell lineSKOV350000 cells per wellNACell titer Glo luminiscent assay10 MOI10% cell viability after 72 hoursNoNoNA No responseNANANANA27119108
OV_4856Myxoma viruswild typeDNAPoxviridaeNoneYesNoNoNAHuman ovarian cancer cell lineSKOV350000 cells per wellNACell titer Glo luminiscent assay10 MOI100% cell viability after 4 daysNoNoNA No responseNANANANA27119108
OV_4857Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoNAHuman ovarian cancer cell lineSKOV350000 cells per wellNACell titer Glo luminiscent assay10 MOI70% cell viability after 4 daysNoNoNA No responseNANANANA27119108
OV_4858Maraba viruswild typeRNARhabdoviridaeNoneYesNoNoNAHuman ovarian cancer cell lineSKOV350000 cells per wellNACell titer Glo luminiscent assay10 MOI20% cell viability after 4 daysNoNoNA No responseNANANANA27119108
OV_4859Myxoma viruswild typeDNAPoxviridaeNoneYesNoNoNAHuman ovarian cancer cell lineSKOV350000 cells per wellNACell titer Glo luminiscent assay10 MOI100% cell viability after 5 daysNoNoNA No responseNANANANA27119108
OV_4860Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoNAHuman ovarian cancer cell lineSKOV350000 cells per wellNACell titer Glo luminiscent assay10 MOI60% cell viability after 5 daysNoNoNA No responseNANANANA27119108
OV_4861Maraba viruswild typeRNARhabdoviridaeNoneYesNoNoNAHuman ovarian cancer cell lineSKOV350000 cells per wellNACell titer Glo luminiscent assay10 MOI20% cell viability after 5 daysNoNoNA No responseNANANANA27119108
OV_4862Myxoma viruswild typeDNAPoxviridaeNoneYesNoNoNAHuman ovarian cancer cell lineOVCAR850000 cells per wellNACell titer Glo luminiscent assay10 MOI100% cell viability after 24 hoursNoNoNA No responseNANANANA27119108
OV_4863Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoNAHuman ovarian cancer cell lineOVCAR850000 cells per wellNACell titer Glo luminiscent assay10 MOI100% cell viability after 24 hoursNoNoNA No responseNANANANA27119108
OV_4864Maraba viruswild typeRNARhabdoviridaeNoneYesNoNoNAHuman ovarian cancer cell lineOVCAR850000 cells per wellNACell titer Glo luminiscent assay10 MOI100% cell viability after 24 hoursNoNoNA No responseNANANANA27119108
OV_4865Myxoma viruswild typeDNAPoxviridaeNoneYesNoNoNAHuman ovarian cancer cell lineOVCAR850000 cells per wellNACell titer Glo luminiscent assay10 MOI100% cell viability after 48 hoursNoNoNA No responseNANANANA27119108
OV_4866Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoNAHuman ovarian cancer cell lineOVCAR850000 cells per wellNACell titer Glo luminiscent assay10 MOI60% cell viability after 48 hoursNoNoNA No responseNANANANA27119108
OV_4867Maraba viruswild typeRNARhabdoviridaeNoneYesNoNoNAHuman ovarian cancer cell lineOVCAR850000 cells per wellNACell titer Glo luminiscent assay10 MOI70% cell viability after 48 hoursNoNoNA No responseNANANANA27119108
OV_4868Myxoma viruswild typeDNAPoxviridaeNoneYesNoNoNAHuman ovarian cancer cell lineOVCAR850000 cells per wellNACell titer Glo luminiscent assay10 MOI90% cell viability after 72 hoursNoNoNA No responseNANANANA27119108
OV_4869Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoNAHuman ovarian cancer cell lineOVCAR850000 cells per wellNACell titer Glo luminiscent assay10 MOI40% cell viability after 72 hoursNoNoNA No responseNANANANA27119108
OV_4870Maraba viruswild typeRNARhabdoviridaeNoneYesNoNoNAHuman ovarian cancer cell lineOVCAR850000 cells per wellNACell titer Glo luminiscent assay10 MOI30% cell viability after 72 hoursNoNoNA No responseNANANANA27119108
OV_4871Myxoma viruswild typeDNAPoxviridaeNoneYesNoNoNAHuman ovarian cancer cell lineOVCAR850000 cells per wellNACell titer Glo luminiscent assay10 MOI100% cell viability after 4 daysNoNoNA No responseNANANANA27119108
OV_4872Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoNAHuman ovarian cancer cell lineOVCAR850000 cells per wellNACell titer Glo luminiscent assay10 MOI30% cell viability after 4 daysNoNoNA No responseNANANANA27119108
OV_4873Maraba viruswild typeRNARhabdoviridaeNoneYesNoNoNAHuman ovarian cancer cell lineOVCAR850000 cells per wellNACell titer Glo luminiscent assay10 MOI25% cell viability after 4 daysNoNoNA No responseNANANANA27119108
OV_4874Myxoma viruswild typeDNAPoxviridaeNoneYesNoNoNAHuman ovarian cancer cell lineOVCAR850000 cells per wellNACell titer Glo luminiscent assay10 MOI100% cell viability after 5 daysNoNoNA No responseNANANANA27119108
OV_4875Vaccinia virusvvDDDNAPoxviridaeDeletion of TK gene and vaccinia growth factorYesNoNoNAHuman ovarian cancer cell lineOVCAR850000 cells per wellNACell titer Glo luminiscent assay10 MOI25% cell viability after 5 daysNoNoNA No responseNANANANA27119108
OV_4876Maraba viruswild typeRNARhabdoviridaeNoneYesNoNoNAHuman ovarian cancer cell lineOVCAR850000 cells per wellNACell titer Glo luminiscent assay10 MOI25% cell viability after 5 daysNoNoNA No responseNANANANA27119108
OV_5160Vesicular stomatitis virusVSV-deltaGPRNARhabdoviridaeVirus lacking envelope protein GYesNoNoUniversity of viennaHuman ovarian cancer cell lineA27801.0E+5 cells per wellNAWST-1 assay1 MOI40% cell viable after 24 hoursNoNoNA No responseNANANANA27738655
OV_5161Vesicular stomatitis virusVSV-MqdeltaGRNARhabdoviridaeAttenuated strain with 4 mutation in M protein and lacking G proteinYesNoNoUniversity of viennaHuman ovarian cancer cell lineA27801.0E+5 cells per wellNAWST-1 assay1 MOI60% cell viable after 24 hoursNoNoNA No responseNANANANA27738655
OV_5162Vesicular stomatitis virusVSV-deltaGPRNARhabdoviridaeVirus lacking envelope protein GYesNoNoUniversity of viennaHuman ovarian cancer cell lineA27801.0E+5 cells per wellNAWST-1 assay1 MOI100% cell killing after 48 hoursNoNoNA No responseNANANANA27738655
OV_5163Vesicular stomatitis virusVSV-MqdeltaGRNARhabdoviridaeAttenuated strain with 4 mutation in M protein and lacking G proteinYesNoNoUniversity of viennaHuman ovarian cancer cell lineA27801.0E+5 cells per wellNAWST-1 assay1 MOI100% cell killing after 48 hoursNoNoNA No responseNANANANA27738655
OV_5164Vesicular stomatitis virusVSV-deltaGPRNARhabdoviridaeVirus lacking envelope protein GYesNoNoUniversity of viennaHuman ovarian cancer cell lineSKOV61.0E+5 cells per wellNAWST-1 assay1 MOI70% cell viable after 24 hoursNoNoNA No responseNANANANA27738655
OV_5165Vesicular stomatitis virusVSV-MqdeltaGRNARhabdoviridaeAttenuated strain with 4 mutation in M protein and lacking G proteinYesNoNoUniversity of viennaHuman ovarian cancer cell lineSKOV61.0E+5 cells per wellNAWST-1 assay1 MOI70% cell viable after 24 hoursNoNoNA No responseNANANANA27738655
OV_5166Vesicular stomatitis virusVSV-deltaGPRNARhabdoviridaeVirus lacking envelope protein GYesNoNoUniversity of viennaHuman ovarian cancer cell lineSKOV61.0E+5 cells per wellNAWST-1 assay1 MOI30% cell viable after 48 hoursNoNoNA No responseNANANANA27738655
OV_5167Vesicular stomatitis virusVSV-MqdeltaGRNARhabdoviridaeAttenuated strain with 4 mutation in M protein and lacking G proteinYesNoNoUniversity of viennaHuman ovarian cancer cell lineSKOV61.0E+5 cells per wellNAWST-1 assay1 MOI20% cell viable after 48 hoursNoNoNA No responseNANANANA27738655
OV_5168Vesicular stomatitis virusVSV-deltaGPRNARhabdoviridaeVirus lacking envelope protein GYesNoNoUniversity of viennaHuman ovarian cancer cell lineSKOV61.0E+5 cells per wellNAWST-1 assay1 MOI10% cell viable after 72 hoursNoNoNA No responseNANANANA27738655
OV_5169Vesicular stomatitis virusVSV-MqdeltaGRNARhabdoviridaeAttenuated strain with 4 mutation in M protein and lacking G proteinYesNoNoUniversity of viennaHuman ovarian cancer cell lineSKOV61.0E+5 cells per wellNAWST-1 assay1 MOI15% cell viable after 72 hoursNoNoNA No responseNANANANA27738655
OV_5170Vesicular stomatitis virusVSV-deltaGPRNARhabdoviridaeVirus lacking envelope protein GYesNoNoUniversity of viennaHuman ovarian cancer cell lineHOC71.0E+5 cells per wellNAWST-1 assay1 MOI90% cell viable after 24 hoursNoNoNA No responseNANANANA27738655
OV_5171Vesicular stomatitis virusVSV-MqdeltaGRNARhabdoviridaeAttenuated strain with 4 mutation in M protein and lacking G proteinYesNoNoUniversity of viennaHuman ovarian cancer cell lineHOC71.0E+5 cells per wellNAWST-1 assay1 MOI90% cell viable after 24 hoursNoNoNA No responseNANANANA27738655
OV_5172Vesicular stomatitis virusVSV-deltaGPRNARhabdoviridaeVirus lacking envelope protein GYesNoNoUniversity of viennaHuman ovarian cancer cell lineHOC71.0E+5 cells per wellNAWST-1 assay1 MOI60% cell viable after 48 hoursNoNoNA No responseNANANANA27738655
OV_5173Vesicular stomatitis virusVSV-MqdeltaGRNARhabdoviridaeAttenuated strain with 4 mutation in M protein and lacking G proteinYesNoNoUniversity of viennaHuman ovarian cancer cell lineHOC71.0E+5 cells per wellNAWST-1 assay1 MOI50% cell viable after 48 hoursNoNoNA No responseNANANANA27738655
OV_5174Vesicular stomatitis virusVSV-deltaGPRNARhabdoviridaeVirus lacking envelope protein GYesNoNoUniversity of viennaHuman ovarian cancer cell lineHOC71.0E+5 cells per wellNAWST-1 assay1 MOI40% cell viable after 72 hoursNoNoNA No responseNANANANA27738655
OV_5175Vesicular stomatitis virusVSV-MqdeltaGRNARhabdoviridaeAttenuated strain with 4 mutation in M protein and lacking G proteinYesNoNoUniversity of viennaHuman ovarian cancer cell lineHOC71.0E+5 cells per wellNAWST-1 assay1 MOI40% cell viable after 72 hoursNoNoNA No responseNANANANA27738655
OV_5176Vesicular stomatitis virusVSV-deltaGPRNARhabdoviridaeVirus lacking envelope protein GYesNoNoATCCHuman ovarian cancer cell lineOVCAR31.0E+5 cells per wellNAWST-1 assay1 MOI100% cell viable after 24 hoursNoNoNA No responseNANANANA27738655
OV_5177Vesicular stomatitis virusVSV-MqdeltaGRNARhabdoviridaeAttenuated strain with 4 mutation in M protein and lacking G proteinYesNoNoATCCHuman ovarian cancer cell lineOVCAR31.0E+5 cells per wellNAWST-1 assay1 MOI100% cell viable after 24 hoursNoNoNA No responseNANANANA27738655
OV_5178Vesicular stomatitis virusVSV-deltaGPRNARhabdoviridaeVirus lacking envelope protein GYesNoNoATCCHuman ovarian cancer cell lineOVCAR31.0E+5 cells per wellNAWST-1 assay1 MOI100% cell viable after 48 hoursNoNoNA No responseNANANANA27738655
OV_5179Vesicular stomatitis virusVSV-MqdeltaGRNARhabdoviridaeAttenuated strain with 4 mutation in M protein and lacking G proteinYesNoNoATCCHuman ovarian cancer cell lineOVCAR31.0E+5 cells per wellNAWST-1 assay1 MOI20% cell viable after 48 hoursNoNoNA No responseNANANANA27738655
OV_5180Vesicular stomatitis virusVSV-deltaGPRNARhabdoviridaeVirus lacking envelope protein GYesNoNoATCCHuman ovarian cancer cell lineOVCAR31.0E+5 cells per wellNAWST-1 assay1 MOI80% cell viable after 72 hoursNoNoNA No responseNANANANA27738655
OV_5181Vesicular stomatitis virusVSV-MqdeltaGRNARhabdoviridaeAttenuated strain with 4 mutation in M protein and lacking G proteinYesNoNoATCCHuman ovarian cancer cell lineOVCAR31.0E+5 cells per wellNAWST-1 assay1 MOI10% cell viable after 72 hoursNoNoNA No responseNANANANA27738655
OV_5284Herpes simplex virusM032DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneYesNoVirus expressing murine IL-12NAHuman ovarian cancer cell lineA27804000 cells per wellNAAlamar blue assay0.1 PFU85% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5285Herpes simplex virusM032DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneYesNoVirus expressing murine IL-12NAHuman ovarian cancer cell lineA27804000 cells per wellNAAlamar blue assay0.33 PFU70% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5286Herpes simplex virusM032DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneYesNoVirus expressing murine IL-12NAHuman ovarian cancer cell lineA27804000 cells per wellNAAlamar blue assay1 PFU42% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5287Herpes simplex virusM032DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneYesNoVirus expressing murine IL-12NAHuman ovarian cancer cell lineA27804000 cells per wellNAAlamar blue assay3.3 PFU10% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5288Herpes simplex virusM032DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneYesNoVirus expressing murine IL-12NAHuman ovarian cancer cell lineA27804000 cells per wellNAAlamar blue assay10 PFU5% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5289Herpes simplex virusM032DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneYesNoVirus expressing murine IL-12NAHuman ovarian cancer cell lineA27804000 cells per wellNAAlamar blue assay33 PFU100% cell killingNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5290Herpes simplex virusM032DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneYesNoVirus expressing murine IL-12NAHuman ovarian cancer cell lineA27804000 cells per wellNAAlamar blue assay100 PFU100% cell killingNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5291Herpes simplex virusM032DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneYesNoVirus expressing murine IL-12NAHuman ovarian cancer cell lineHeyA84000 cells per wellNAAlamar blue assay0.1 PFU100% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5292Herpes simplex virusM032DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneYesNoVirus expressing murine IL-12NAHuman ovarian cancer cell lineHeyA84000 cells per wellNAAlamar blue assay0.33 PFU98% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5293Herpes simplex virusM032DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneYesNoVirus expressing murine IL-12NAHuman ovarian cancer cell lineHeyA84000 cells per wellNAAlamar blue assay1 PFU95% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5294Herpes simplex virusM032DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneYesNoVirus expressing murine IL-12NAHuman ovarian cancer cell lineHeyA84000 cells per wellNAAlamar blue assay3.3 PFU77% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5295Herpes simplex virusM032DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneYesNoVirus expressing murine IL-12NAHuman ovarian cancer cell lineHeyA84000 cells per wellNAAlamar blue assay10 PFU60% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5296Herpes simplex virusM032DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneYesNoVirus expressing murine IL-12NAHuman ovarian cancer cell lineHeyA84000 cells per wellNAAlamar blue assay33 PFU39% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5297Herpes simplex virusM032DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneYesNoVirus expressing murine IL-12NAHuman ovarian cancer cell lineHeyA84000 cells per wellNAAlamar blue assay100 PFU22% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5298Herpes simplex virusM032DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneYesNoVirus expressing murine IL-12NAHuman ovarian cancer cell lineHEYA8 MDR4000 cells per wellNAAlamar blue assay0.1 PFU100% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5299Herpes simplex virusM032DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneYesNoVirus expressing murine IL-12NAHuman ovarian cancer cell lineHEYA8 MDR4000 cells per wellNAAlamar blue assay0.33 PFU38% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5300Herpes simplex virusM032DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneYesNoVirus expressing murine IL-12NAHuman ovarian cancer cell lineHEYA8 MDR4000 cells per wellNAAlamar blue assay1 PFU10% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5301Herpes simplex virusM032DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneYesNoVirus expressing murine IL-12NAHuman ovarian cancer cell lineHEYA8 MDR4000 cells per wellNAAlamar blue assay3.3 PFU100% cell killingNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5302Herpes simplex virusM032DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneYesNoVirus expressing murine IL-12NAHuman ovarian cancer cell lineHEYA8 MDR4000 cells per wellNAAlamar blue assay10 PFU100% cell killingNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5303Herpes simplex virusM032DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneYesNoVirus expressing murine IL-12NAHuman ovarian cancer cell lineHEYA8 MDR4000 cells per wellNAAlamar blue assay33 PFU100% cell killingNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5304Herpes simplex virusM032DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneYesNoVirus expressing murine IL-12NAHuman ovarian cancer cell lineHEYA8 MDR4000 cells per wellNAAlamar blue assay100 PFU100% cell killingNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5305Herpes simplex virusM032DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneYesNoVirus expressing murine IL-12NAHuman ovarian cancer cell lineSKOV34000 cells per wellNAAlamar blue assay0.1 PFU100% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5306Herpes simplex virusM032DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneYesNoVirus expressing murine IL-12NAHuman ovarian cancer cell lineSKOV34000 cells per wellNAAlamar blue assay0.33 PFU98% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5307Herpes simplex virusM032DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneYesNoVirus expressing murine IL-12NAHuman ovarian cancer cell lineSKOV34000 cells per wellNAAlamar blue assay1 PFU50% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5308Herpes simplex virusM032DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneYesNoVirus expressing murine IL-12NAHuman ovarian cancer cell lineSKOV34000 cells per wellNAAlamar blue assay3.3 PFU18% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5309Herpes simplex virusM032DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneYesNoVirus expressing murine IL-12NAHuman ovarian cancer cell lineSKOV34000 cells per wellNAAlamar blue assay10 PFU15% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5310Herpes simplex virusM032DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneYesNoVirus expressing murine IL-12NAHuman ovarian cancer cell lineSKOV34000 cells per wellNAAlamar blue assay33 PFU100% cell killingNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5311Herpes simplex virusM032DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing human IL-12 geneYesNoVirus expressing murine IL-12NAHuman ovarian cancer cell lineSKOV34000 cells per wellNAAlamar blue assay100 PFU100% cell killingNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5608Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman ovarian sarcoma cell lineSW62680% confluencyNAMTT assay4 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5609Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman ovarian sarcoma cell linePA-180% confluencyNAMTT assay4 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5610Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman ovarian sarcoma cell lineES-280% confluencyNAMTT assay13 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5611Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman ovarian sarcoma cell lineSKOV380% confluencyNAMTT assay24 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5612Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman ovarian sarcoma cell lineOVCAR380% confluencyNAMTT assay34 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5827Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman ovarian carcinoma cell lineSW2680% confluencyNANA4 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5828Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman ovarian carcinoma cell linePA-180% confluencyNANA4 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578