Welcome to the homepage of MucormyDB
The Mucormydb is a web server that enables the scientific community to fight against opportunistic fungal infections caused by a group of molds. We have listed the Mucorales species that are known to cause mucormycosis here, along with genomic and proteomic information, diagnostic options, and FDA-approved or drug options. A few video lectures and a link to relevant literature have also been given. Additionally, we made an effort to suggest possible pharmacological compounds and therapeutic options that could aid in the treatment of mucormycosis. The website seeks to give comprehensive information to the scientific community on a single platform so they can deal with fatal diseases.
Cite: Tomar R, Patiyal S, Kaur D, Choudhary S and Raghava GPS (2024) Genome-based solutions for managing mucormycosis. Advances in Protein Chemistry and Structural Biology. doi.org/10.1016/bs.apcsb.2023.11.014.Major Modules
Genomics/Proteomics: This module contains information about the whole genome, nucleotide, and protein sequences of the species belonging to the order Mucorales. The user may download information (available at NCBI) about the given species from this page.
Immunotherapy: This module contains information about the putative sequence-based therapeutics predicted using well-established tools such as “desiRM”, “LBTope”, “CTLpred”, “IL-10pred”, “Propred”, “VaccineDA” and many more. The user may download potential vaccine candidates from this module.
Drugs: This module provides the information about the available drugs given in the literature as well as FDA-approved with their DrugBank ID, the potential drug molecules and the tertiary structures of the fungal proteins that are responsible for the survival of fungal cells and invasion into the host body.The tertiary structure predicted using Alphafold2.0.