Chirality browse result page of CPPsite: A database of cell penetrating peptides

ID	PMID	Sequence	Chirality	Peptide name	Origin	Family	Nature	Sub-cellular localization	N terminal modification	C terminal modification	Uptake efficiency	Uptake mechanism	Cancer cell lines	Patent number
1044	10930519	GWTLNSAGYLLGKINLKALAALAKKIL	L	Transportan (TP)	Fusion of Neropeptide Galanin and wasp venom pepti	Chimeric	Amphipathic	Cytoplasm and nucleus and intracellular membranous structures	Biotinylation	Free	High	Non-receptor mediated endocytic pathway	Human bowes melanoma cells	Unknown
1045	10930519	GWTLNSAGYLLGKINLKALAALAKKLL	L	TP2	Fusion of Neropeptide Galanin and wasp venom pepti	Chimeric	Amphipathic	Cytoplasm and nucleus and intracellular membranous structures	Biotinylated at amino group of Lys	Free	Unknown	Probably non-receptor mediated endocytic pathway	Human bowes melanoma cells	Unknown
1046	10930519	GWTLNSAGYLLGKFLPLILRKIVTAL	L	TP4	Fusion of Neropeptide Galanin and wasp venom pepti	Chimeric	Amphipathic	Cytoplasm and nucleus and intracellular membranous structures	Biotinylated at amino group of Lys	Free	Unknown	Probably non-receptor mediated endocytic pathway	Human bowes melanoma cells	Unknown
1047	10930519	GWTLNPAGYLLGKINLKALAALAKKIL	L	TP5	Fusion of Neropeptide Galanin and wasp venom pepti	Chimeric	Amphipathic	Cytoplasm and nucleus and intracellular membranous structures	Biotinylated at amino group of Lys	Free	Unknown	Probably non-receptor mediated endocytic pathway	Human bowes melanoma cells	Unknown
1048	10930519	GWTLNPPGYLLGKINLKALAALAKKIL	L	TP6	Fusion of Neropeptide Galanin and wasp venom pepti	Chimeric	Amphipathic	Cytoplasm and nucleus and intracellular membranous structures	Biotinylated at amino group of Lys	Free	Unknown	Probably non-receptor mediated endocytic pathway	Human bowes melanoma cells	Unknown
1049	10930519	LNSAGYLLGKINLKALAALAKKIL	L	TP7	Fusion of Neropeptide Galanin and wasp venom pepti	Chimeric	Amphipathic	Cytoplasm and nucleus and intracellular membranous structures	Biotinylated at amino group of Lys	Free	Comparable to Transportan	Probably non-receptor mediated endocytic pathway	Human bowes melanoma cells	Unknown
1050	10930519	LLGKINLKALAALAKKIL	L	TP8	Fusion of Neropeptide Galanin and wasp venom pepti	Chimeric	Amphipathic	Cytoplasm and nucleus and intracellular membranous structures	Biotinylated at amino group of Lys	Free	Very low relative to Transportan	Probably non-receptor mediated endocytic pathway	Human bowes melanoma cells	Unknown
1051	10930519	GWTLNSAGYLLGKLKALAALAKKIL	L	TP9	Fusion of Neropeptide Galanin and wasp venom pepti	Chimeric	Amphipathic	Cytoplasm and nucleus and intracellular membranous structures	Biotinylated at amino group of Lys	Free	Comparable to Transportan	Probably non-receptor mediated endocytic pathway	Human bowes melanoma cells	Unknown
1052	10930519	AGYLLGKINLKALAALAKKIL	L	TP10	Fusion of Neropeptide Galanin and wasp venom pepti	Chimeric	Amphipathic	Cytoplasm and nucleus and intracellular membranous structures	Biotinylated at amino group of Lys	Free	Comparable to Transportan	Probably non-receptor mediated endocytic pathway	Human bowes melanoma cells	Unknown
1053	10930519	GWTLNSKINLKALAALAKKIL	L	TP11	Fusion of Neropeptide Galanin and wasp venom pepti	Chimeric	Amphipathic	Cytoplasm and nucleus and intracellular membranous structures	Biotinylated at amino group of Lys	Free	Lower than Transportan	Probably non-receptor mediated endocytic pathway	Human bowes melanoma cells	Unknown
1054	10930519	LNSAGYLLGKLKALAALAKIL	L	TP12	Fusion of Neropeptide Galanin and wasp venom pepti	Chimeric	Amphipathic	Cytoplasm and nucleus and intracellular membranous structures	Biotinylated at amino group of Lys	Free	Lower than Transportan	Probably non-receptor mediated endocytic pathway	Human bowes melanoma cells	Unknown
1055	10930519	LNSAGYLLGKALAALAKKIL	L	TP13	Fusion of Neropeptide Galanin and wasp venom pepti	Chimeric	Amphipathic	Cytoplasm and nucleus and intracellular membranous structures	Biotinylated at amino group of Lys	Free	Very low relative to Transportan	Probably non-receptor mediated endocytic pathway	Human bowes melanoma cells	Unknown
1056	10930519	AGYLLGKLKALAALAKKIL	L	TP14	Fusion of Neropeptide Galanin and wasp venom pepti	Chimeric	Amphipathic	Cytoplasm and nucleus and intracellular membranous structures	Biotinylated at amino group of Lys	Free	Lower than Transportan	Probably non-receptor mediated endocytic pathway	Human bowes melanoma cells	Unknown
1057	10930519	LNSAGYLLGKLKALAALAK	L	TP15	Fusion of Neropeptide Galanin and wasp venom pepti	Chimeric	Amphipathic	Cytoplasm and nucleus and intracellular membranous structures	Biotinylated at amino group of Lys	Free	Very low relative to Transportan	Probably non-receptor mediated endocytic pathway	Human bowes melanoma cells	Unknown
1058	10930519	GWTLNSAGYLLGKINLKAPAALAKKIL	L	TP16	Fusion of Neropeptide Galanin and wasp venom pepti	Chimeric	Amphipathic	Cytoplasm and nucleus and intracellular membranous structures	Biotinylated at amino group of Lys	Free	Unknown	Probably non-receptor mediated endocytic pathway	Human bowes melanoma cells	Unknown
1389	17984975	AGYLLGKINLKALAALAKKIL	L	TP10	Fusion of Neropeptide Galanin and wasp venom pepti	Chimeric	Amphipathic	Unknown	Labelled with fluorescein at amino group of lysine	Amidation	Unknown	Unknown	MCF-7 and MDA MB 231	Unknown
1417	11731788	KETWWETWWTEWSQPKKKRKV	L	Pep-1	Trp rich cluster + SV40 NLS	Chimeric	Amphipathic	Nucleus	Acetylation	Cysteamide at C-Terminus (FITC labelling)	Unknown	Non-endocytic pathway	HS-68 and NIH-3T3	Unknown
1418	20188697	KETWFETWFTEWSQPKKKRKV	L	Pep-2	Trp rich cluster + SV40 NLS	Chimeric	Amphipathic	Probably nucleus	Acetylation	Cysteamide at C-Terminus (FITC labelling)	Unknown	Probably non-endocytic pathway	HeLa	Unknown
1419	20188697	KWFETWFTEWPKKRK	L	Pep-3	Trp rich cluster + SV40 NLS	Chimeric	Amphipathic	Probably nucleus	Acetylation	Cysteamide at C-Terminus (FITC labelling)	Unknown	Probably non-endocytic pathway	HeLa	Unknown
1423	12771197	GALFLGFLGAAGSTMGAWSQPKKKRKV	L	MPG	HIV GP41 + SV 40 NLS	Chimeric	Amphipathic	Nucleus	Acetylation	Cysteamide at C-Terminus	Unknown	Non-endocytic pathway	HS-68, Cos-7 and HeLa	Unknown
1424	12771197	GALFLGFLGAAGSTMGAWSQPKSKRKV	L	MPG Mutant	HIV GP41 + SV 40 NLS	Chimeric	Amphipathic	Nucleus	Acetylation	Cysteamide at C-Terminus	Lower than wilde type MPG	Non-endocytic pathway	HS-68, Cos-7 and HeLa	Unknown
1433	12119035	ALWKTLLKKVLKAPKKKRKV	L	S4(13)-PV	Dermaseptin S4 peptide + SV40 NLS	Chimeric	Karyophilic	Cytoplasm and nucleus	Labelled rhodamine	Amidation	Unknown	Non-endocytic pathway	HeLa	US 20040132970
1434	12119035	PKKKRKVALWKTLLKKVLKA	L	PV-S4(13)	SV40 NLS + dermaseptin S4 peptide	Chimeric	Karyophilic	Cytoplasm and nucleus	Labelled rhodamine	Amidation	Unknown	Non-endocytic pathway	HeLa	US 20040132970
1435	12119035	VKRKKKPALWKTLLKKVLKA	L	PV reverse-S4(13)	Dermaseptin S4 peptide + SV40 NLS reverse	Chimeric	Unknown	Cytoplasm	Labelled rhodamine	Amidation	Unknown	Non-endocytic pathway	HeLa	US 20040132970
1436	12119035	RQARRNRRRALWKTLLKKVLKA	L	RR-S4(13)	Rev ARM + Dermaseptin S4 peptide	Chimeric	Karyophilic	Cytoplasm and nucleus	Labelled rhodamine	Amidation	Unknown	Non-endocytic pathway	HeLa	US 20040132970
1439	21029412	EEEAAGRKRKKRT	L	Glu-Oct-6	Transcription factor Oct-6 based chimeric peptide	Chimeric	Unknown	Cytoplasm and nucleus	Free	Labelled with FITC	High relative to Oct-6	Energy dependent pathway	DU-145 and LNCaP	US 20100137187
1444	21029412	FFFAAGRKRKKRT	L	Phe-Oct-6	Transcription factor Oct-6 based chimeric peptide	Chimeric	Cationic	Cytoplasm and nucleus	Free	Labelled with FITC	Low	Probably energy dependent pathway	DU-145 and LNCaP	US 20100137187
1445	21029412	NNNAAGRKRKKRT	L	Asn-Oct-6	Transcription factor Oct-6 based chimeric peptide	Chimeric	Cationic	Cytoplasm and nucleus	Free	Labelled with FITC	Low	Probably energy dependent pathway	DU-145 and LNCaP	US 20100137187
1446	21029412	YYYAAGRKRKKRT	L	Tyr-Oct-6	Transcription factor Oct-6 based chimeric peptide	Chimeric	Cationic	Cytoplasm and nucleus	Free	Labelled with FITC	Low	Probably energy dependent pathway	DU-145 and LNCaP	US 20100137187
1449	17622242	AGYLLGKINLKALAALAKKIL	L	TP10	Fusion of Neropeptide Galanin and wasp venom pepti	Chimeric	Amphipathic	Unknown	Labelled with fluoresceine at amino group of lysin	Amidation	Comparable to Penetratin	Unknown	HeLa, CHO K2	Unknown
1501	15461515	GALFLGFLGAAGSTMGAWSQPKKKRKV	L	P(beta)	gp41-SV40	Chimeric	Amphipathic	Unknown	Acetylation	Cysteamide group	Unknown	Unknown	Unknown	Unknown
1502	15461515	GALFLAFLAAALSLMGLWSQPKKKRRV	L	P(alpha)	gp41-SV40	Chimeric	Amphipathic	Unknown	Acetylation	Cysteamide group	Unknown	Unknown	Unknown	Unknown
1507	Unknown	GLLEALAELLEGLRKRLRKFRNKIKEK	L	N-E5L-Sc18	N-terminal region of the HA2 subunit + Sc18	Chimeric	Unknown	Cytosol and nucleus	Labelled with fluoresceine	Amidation	Unknown	Endocytic pathway	HeLa, HEK 293 and MCF-8	Unknown
1539	7782278	AAVALLPAVLLALLAPEILLPNNYNAYESYKYPGMFIALSK	L	SKP	Signal sequence of K-FGF + C-terminal region of (1	Chimeric	Unknown	Unknown	Tyrosine radiolabeling with Iodine 125	Free	Unknown	Non-receptor mediated import mechanism	NIH-3T3	Unknown
1540	7782278	AAVALLPAVLLALLAPVQRKRQKLMP	L	SN50	Signal sequence of K-FGF + NLS of NF-kB p50 subuni	Chimeric	Unknown	Unknown	Unknown	Unknown	Unknown	Unknown	LE-II cells	Unknown
1542	9287160	MGLGLHLLVLAAALQGAWSQPKKKRKV	L	Peptide 1	Designed (Signal sequence + NLS)	Chimeric	Amphipathic	Nucleus	Acetylation	Cysteamide	Unknown	Non-endocytic pathway (direct translocation)	HS-68 Cells	Unknown
1543	9287160	MGLGLHLLVLAAALQGAKKKRKV	L	Peptide 2	Designed (Signal sequence + NLS)	Chimeric	Amphipathic	Nucleus	Acetylation	Cysteamide	Unknown	Non-endocytic pathway (direct translocation)	HS-68 Cells	Unknown
1788	11923291	AAVALLPAVLLALLAKKNNLKDCGLF	L	MPS-Galphai2	MPS + C-terminal of Galphai2	Chimeric	Unknown	Unknown	Unknown	Unknown	Unknown	Unknown	BAE cells	Unknown
1789	11923291	AAVALLPAVLLALLAKKNNLKECGLY	L	MPS-Galphai3	MPS + C-terminal of Galphai3	Chimeric	Unknown	Unknown	Unknown	Unknown	Unknown	Unknown	BAE cells	Unknown
1790	11923291	AAVALLPAVLLALLAVTDQLGEDFFAVDLEAFLQEFGLLPEKE	L	Anti-BetaGamma	MPS - Phosducin - like protein C terminus	Chimeric	Unknown	Unknown	Unknown	Unknown	Unknown	Unknown	BAE cells	Unknown
1807	15937518	AGYLLGKINLKALAALAKKIL	L	Transportan	Fusion of Neropeptide Galanin and wasp venom pepti	Chimeric	Amphipathic	Unknown	Rhodamine-labelled	Free	Less than polyarginine and pAntp but equal to Tat	Unknown	CHO K1, HeLa, A549 cells	Unknown
1808	15937518	AGYLLGKINLKALAALAKKILTYADFIASGRTGRRNAI	L	Transportan-PKI	Galanin-mastoparan and protein kinase Inhibitor	Chimeric	Unknown	Unknown	Rhodamine-labelled	Free	Equal to Polyarginine-PKI and less than pAntp-PKI,	Unknown	CHO K1, HeLa, A549 cells	Unknown
1810	15937518	RRRRRRRRRRRTYADFIASGRTGRRNAI	L	R11-PKI	Oligoarginine and Protein Kinase Inhibitor	Chimeric	Unknown	Unknown	Rhodamine-labelled	Free	Greater than pAntp-PKI, Tat-PKI but equal to trans	Unknown	CHO K1, HeLa, A549 cells	Unknown

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