Details of CPPsite entry with Sequence KKLFKKILKKL |
Primary information | |
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PEPTIDE SEQUENCE | KKLFKKILKKL |
CPPsite ID | 2337, 2339, |
PEPTIDE NAME | CF-BP16, BP326 |
CHIRALITY | L, L |
LINEAR/CYCLIC | Linear, Linear |
SOURCE | Synthetic, Synthetic |
CATEGORY | Cationic, Cationic |
SUB CELLULAR LOCALIZATION | Cytoplasm, Cytoplasm |
N-TERMINAL MODIFICATION | Free, Free |
C-TERMINAL MODIFICATION | Amidation, Amidation |
CHEMICAL MODIFICATION | NA, NA |
UPTAKE EFFICIENCY | High (compare to Tat), High (similar to that of CF-BP16) |
PROPOSED UPTAKE MECHANISM | Clathrin dependent endocytosis, NA |
INVITRO/INVIVO | In vitro, In vitro |
CELL LINE | MCF-7, CAPAN-1 and mouse embryonic fibroblast 3T3, MCF-7, CAPAN-1 and mouse embryonic fibroblast 3T3 |
In VIVO MODEL | NA, NA |
CARGO | Fluorophore [5(6)-carboxyfluorescein (CF)], Fluorophore [5(6)-carboxyfluorescein (CF)], CLB |
PMID | 24480922, 24480922 |
PATENT | Unknown, Unknown |
Tertiary Structure (Technique) | 2337 (PEPstrMOD), 2339 (PEPstrMOD), |