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Details of CPPsite entry with Sequence HHHHHHHHRRRRRRRRRRRRRRR
Primary information
PEPTIDE SEQUENCEHHHHHHHHRRRRRRRRRRRRRRR
CPPsite ID 2135, 2136,
PEPTIDE NAMEH8R15, STR-H8R15
CHIRALITYL, L
LINEAR/CYCLICLinear, Linear
SOURCESynthetic, Synthetic
CATEGORYCationic, Cationic
SUB CELLULAR LOCALIZATIONCytoplasm, Cytoplasm
N-TERMINAL MODIFICATIONAcetylation, Stearylation
C-TERMINAL MODIFICATIONAmidation, Amidation
CHEMICAL MODIFICATIONNA, NA
UPTAKE EFFICIENCYNA, STR-H8R15/GAPDH siRNA formulations revealed decreased mRNA levels by 17% at R/P 10, lower than that of STR-H8R8
PROPOSED UPTAKE MECHANISMEndocytosis, Endocytosis
INVITRO/INVIVOIn vitro, In vitro
CELL LINECHO-K1 cells, HeLa, CHO-K1 cells, HeLa
In VIVO MODELNA, NA
CARGONucleic acid (GAPDH siRNA), Nucleic acid (GAPDH siRNA)
PMID25193363, 25193363
PATENTUnknown, Unknown
Tertiary Structure
(Technique)		2135 (PEPstrMOD), 2136 (PEPstrMOD),