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Details of CPPsite entry with Sequence GYGRKKRRQRRRG
Primary information
PEPTIDE SEQUENCEGYGRKKRRQRRRG
CPPsite ID 1463, 1464, 1465,
PEPTIDE NAMETat (47-57), Tat (47-57), Tat (47-57)
CHIRALITYL, L, L
LINEAR/CYCLICLinear, Linear, Linear
SOURCEProtein derived, Protein derived, Protein derived
CATEGORYCationic, Cationic, Cationic
SUB CELLULAR LOCALIZATIONCytoplasmic and punctuated pattern (vesicles), Punctuated cytoplasmic (vesicles) as well as extracellular staining, Mainly extracellular staining
N-TERMINAL MODIFICATIONCarries an extra glycine and conjugation with fluores, Carries an extra glycine and Conjugation with fluores, Carries an extra glycine and Conjugation with fluores
C-TERMINAL MODIFICATIONCarries an extra glycine, Carries an extra glycine, Carries an extra glycine
CHEMICAL MODIFICATIONNA, NA, NA
UPTAKE EFFICIENCYUnknown, Unknown, Unknown
PROPOSED UPTAKE MECHANISMCondition dependent (not determined in this paper), Condition dependent (not determined in this paper), Condition dependent (not determined in this paper)
INVITRO/INVIVOIn vitro, In vitro, In vitro
CELL LINEMDCK cells, Calu-3 cells, TR146 cells
In VIVO MODELNA, NA, NA
CARGOFluorophore (fluorescein), Fluorophore (fluorescein), Fluorophore (fluorescein)
PMID15290867, 15290867, 15290867
PATENTUnknown, Unknown, Unknown
Tertiary Structure
(Technique)
1463 (PEPstrMOD), 1464 (PEPstrMOD), 1465 (PEPstrMOD),