Details of CPPsite entry with Sequence GYGRKKRRQRRRG |
Primary information | |
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PEPTIDE SEQUENCE | GYGRKKRRQRRRG |
CPPsite ID | 1463, 1464, 1465, |
PEPTIDE NAME | Tat (47-57), Tat (47-57), Tat (47-57) |
CHIRALITY | L, L, L |
LINEAR/CYCLIC | Linear, Linear, Linear |
SOURCE | Protein derived, Protein derived, Protein derived |
CATEGORY | Cationic, Cationic, Cationic |
SUB CELLULAR LOCALIZATION | Cytoplasmic and punctuated pattern (vesicles), Punctuated cytoplasmic (vesicles) as well as extracellular staining, Mainly extracellular staining |
N-TERMINAL MODIFICATION | Carries an extra glycine and conjugation with fluores, Carries an extra glycine and Conjugation with fluores, Carries an extra glycine and Conjugation with fluores |
C-TERMINAL MODIFICATION | Carries an extra glycine, Carries an extra glycine, Carries an extra glycine |
CHEMICAL MODIFICATION | NA, NA, NA |
UPTAKE EFFICIENCY | Unknown, Unknown, Unknown |
PROPOSED UPTAKE MECHANISM | Condition dependent (not determined in this paper), Condition dependent (not determined in this paper), Condition dependent (not determined in this paper) |
INVITRO/INVIVO | In vitro, In vitro, In vitro |
CELL LINE | MDCK cells, Calu-3 cells, TR146 cells |
In VIVO MODEL | NA, NA, NA |
CARGO | Fluorophore (fluorescein), Fluorophore (fluorescein), Fluorophore (fluorescein) |
PMID | 15290867, 15290867, 15290867 |
PATENT | Unknown, Unknown, Unknown |
Tertiary Structure (Technique) | 1463 (PEPstrMOD), 1464 (PEPstrMOD), 1465 (PEPstrMOD), |