Details of CPPsite entry with Sequence GLRKRLRKFRNKIKEK |
Primary information | |
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PEPTIDE SEQUENCE | GLRKRLRKFRNKIKEK |
CPPsite ID | 2601, 1506, |
PEPTIDE NAME | CF-sC18, Sc18 |
CHIRALITY | L, L |
LINEAR/CYCLIC | Linear, Linear |
SOURCE | Synthetic, Protein derived |
CATEGORY | NA, Cationic amphipathic |
SUB CELLULAR LOCALIZATION | Cytoplasmic Vesicles, Vesicles |
N-TERMINAL MODIFICATION | Amidation, Conjugation with fluorescein |
C-TERMINAL MODIFICATION | NA, Amidation |
CHEMICAL MODIFICATION | NA, NA |
UPTAKE EFFICIENCY | NA, High |
PROPOSED UPTAKE MECHANISM | Endocytic pathway, Energy-dependent endocytic pathway |
INVITRO/INVIVO | In vitro, In vitro |
CELL LINE | MCF-7 cells, HeLa, HEK 293 and MCF-7 |
In VIVO MODEL | NA, NA |
CARGO | Fluorophore (Carboxyfluorescein), Fluorophore (fluorescein) |
PMID | 21956822 |
PATENT | Unknown, Unknown |
Tertiary Structure (Technique) | 2601 (PEPstrMOD), 1506 (PEPstrMOD), |