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This page gives details of CPPsite entry with ID 2247
Primary information
CPPsite ID2247
PEPTIDE SEQUENCECyclo (FΦRRRRQ)
PEPTIDE NAMEcFΦR4-PCP
CHIRALITYModified
LINEAR/CYCLICCyclic
SOURCESynthetic
CATEGORYAmphipathic
SUB CELLULAR LOCALIZATIONCytoplasm and Nucleus
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONAmidation
CHEMICAL MODIFICATIONΦ, L-2-naphthylalanine,miniPEG, 8-amino-3,6-dioxaoctanoic acid
UPTAKE EFFICIENCYHigher efficiency
PROPOSED UPTAKE MECHANISMEndocytic pathway
INVITRO/INVIVOIn vitro
CELL LINEHEK293, HeLa, MCF-7, NIH 3T3, A549, Jurkat, H1650, and H1299 cells
CARGOPeptide [PCP, miniPEG-DE(pCAP)LI-NH2]
PMID24896852
PATENTUnknown
LENGTH8
Secondary StructureNA
SMILESNA
3-D StructureNot Predicted