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This page gives details of CPPsite entry with ID 1537
Primary information
CPPsite ID1537
PEPTIDE SEQUENCEGSPWGLQHHPPRT
PEPTIDE NAME439A peptide
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYUnknown
SUB CELLULAR LOCALIZATIONUnknown
N-TERMINAL MODIFICATIONConjugation with FITC
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYOn A431 cells, 10 fold lower than Tat but on HeLa
PROPOSED UPTAKE MECHANISMCaveolae/raft-dependent endocytic process
INVITRO/INVIVOIn vitro
CELL LINEHuman carcinoma A431, HeLa and CHO
CARGOFluorophore (FITC)
PMID17268054
PATENTUnknown
LENGTH13
Secondary StructureCBTTBSSSSSSCC
SMILESNCC(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H]([C@@H](C)O)C=O
Tertiary Structure
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  (PEPstrMOD)