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This page gives details of CPPsite entry with ID 1492
Primary information
CPPsite ID1492
PEPTIDE SEQUENCEGIGKFLHSAKKWGKAFVGQIMNC
PEPTIDE NAMEMG2d
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYAntimicrobial
SUB CELLULAR LOCALIZATIONCytosol
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONConjugation with Texas Red
UPTAKE EFFICIENCYHigher than Tat (47-57)
PROPOSED UPTAKE MECHANISMTransient pore formation-translocation mechanism
INVITRO/INVIVOIn vitro
CELL LINEHeLa or TM12 cells
CARGOFluorophore (Texas Red)
PMID12417587
PATENTUnknown
LENGTH23
Secondary StructureCGGGSTHHHHTTGGGSGGGCSCC
SMILESNCC(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](CO)C(=O)N[C@H](O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](C)C(=O)N[C@@H](CC)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CS)C=O.CC.C.C.C.C.C
Tertiary Structure
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  (PEPstrMOD)