1. Introduction
    1. Architecture of BIAdb
    2. Definition of the scope of the database
    3. Data Source
  2. Web server
  3. Criteria for data collection
  4. Data submission and updates


i. Architecture of BIAdb


ii. Definition of the scope of the database
The 'BIAdb' database contains the following data for each benzyl isoquinoline alkaloid:

  1. Name: It represents the name of the benzyl isoquinoline alkaloid being queried
  2. ID: This is the ID number given by us to all the entries of the databasePubchem ID: This is the PubchemID of that particular entry
  3. KEGG ID: This is the KEGG ID of that particular entry
  4. Source: This is the source of that particular Benzylisoquinoline(BIA) compound
  5. Type: This is the type of that particular BIA compound
  6. Function: This is the function of that particular BIA compound
  7. Molecular formula: This represents the molecular formula of the entry
  8. Molecular weight: This depicts the molecular weight of the entry
  9. Exact mass: This is the exact mass of that particular BIA compound
  10. XLogP: It is the XLogP value of the specific entry
  11. Topological Polar Surface Area: gives the value of TPSA of particular compound
  12. H-Bond Donor: gives number of H-Bond donors in the compound
  13. H-Bond Acceptor:gives number of H-Bond acceptors in compound
  14. Rotational Bond Count: gives number of rotatable bonds in the compound
  15. IUPAC Name: gives the IUPAC name of the benzyl isoquinoline alkaloid
  16. 2-D & 3-D Structure: represents the 2-D & 3-D structures of the entries
  17. Canonical SMILES: Canonical SMILE for the given benzyl isoquinoline alkaloid
  18. Isomeric SMILES: Isomeric SMILE for the given benzyl isoquinoline alkaloid
  19. Drugpedia: This is the external link to the drugpedia developed by our group where the detailed information of the entries in the database can be accessed easily. User can also add or edit the information on pages of particular entries.
  20. References: External link to PubMed references

Our belief is that the BIAdb can be useful to the people working with alkaloids and it can be helpful in the studies of theraupeutic efficacy of the natural alkaloids.

iii. Data Source
The main sources of the data in the BIAdb are:
Data SourceNumber of Entries
Other Sources (literature search)334

The database is up-to-date and is regularly updated to add new entries.


Information regarding the benzyl isoquinoline alkaloids can be retrived through the web server using the: