ID | 1157 |
Name of the vaccine | ProHIBiT |
Microbe | Bacteria |
Disease name | Haemophilus influenzae type b (Hib) |
Name of bacteria | Haemophilus influenzae |
Type of vaccine | Conjugate |
Nucleic acid content | DNA |
Age | 15 months and older |
Description of the vaccine | Haemophilus b Conjugate Vaccine (Diphtheria Toxoid-Conjugate) (PRP-D). |
Name of the manufacturer | Connaught |
Name of the manufacturing country | NA |
Year of manufacture | 1989 |
Clinical Phase status | Approved |
Bacterial strain | Anaerobic gram-negative coccobacillus. |
Efficacy | 90% protective efficacy in children 18 to 71 months. |
Vaccine formulation | Sterile solution |
Dosage | Single injection of 0.5 mL. Primary immunization at 15 months of age or as Booster vaccination at 12 to 15 months. |
Mechanism of action | Induces Anti-capsular antibodies. Antibody concentration of 0.15 µg/mL or more : Protection, 1 µg/mL or more : Long-term protection |
Route of administration | Intramuscular |
Indications | Immunization against invasive diseases caused by Haemophilus influenzae type b. |
Export | ACIP |
Approval | NA |
Adjuvant | NA |
Repurposing | NA |
Side effects of vaccine | Diarrhoea, vomiting, crying, fever, irritability, sleepiness, anorexia, urticaria, seizure, and renal failure. |
Post vaccination | NA |
Dose type | Single dose |
Interspecies transfer | NA |
PubMed identifier | NA |
Clinical trial number | NA |
Reference | https://www.rxlist.com/prohibit-drug.htm#description |
Other name | NA |
Additional Links | https://www.immunize.org/timeline/
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