ID | 1135 |
Name of the vaccine | Mencevax ACWY |
Microbe | Bacteria |
Disease name | Meningococcal disease |
Name of bacteria | Neisseria meningitidis |
Type of vaccine | Subunit |
Nucleic acid content | DNA |
Age | Over 2 years |
Description of the vaccine | Meningococcus serogroup A, C, W-135 and Y vaccine. |
Name of the manufacturer | GlaxoSmithKline Biologicals |
Name of the manufacturing country | Belgium |
Year of manufacture | NA |
Clinical Phase status | Approved |
Bacterial strain | Gram-negative diplococcus. |
Efficacy | Vaccine effectiveness against serogroup A and W-135 was 95.8%. |
Vaccine formulation | Powder and diluent for solution for injection. |
Dosage | Single dose (0.5 mL).
Children who were aged under 5 years should be revaccinated every 2-3 years (if high risk). |
Mechanism of action | Induces bactericidal antibodies against meningococci of the serogroups A, C, W-135 and Y. |
Route of administration | Subcutaneous |
Indications | Recommended for people at risk and those living in closed communities and contacts of patients with disease. |
Export | NA |
Approval | NA |
Adjuvant | NA |
Repurposing | NA |
Side effects of vaccine | Irritability, drowsiness, headache, pain and redness at the injection site, fatigue. |
Post vaccination | NA |
Dose type | Single dose |
Interspecies transfer | NA |
PubMed identifier | NA |
Clinical trial number | NA |
Reference | https://www.fda.moph.go.th/sites/drug/Summary/2C_5_53_B_Mencevax%20ACWY.pdf |
Other name | NA |
Additional Links | NA
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