ID | 1121 |
Name of the vaccine | Zyvac TCV |
Microbe | Bacteria |
Disease name | Typhoid |
Name of bacteria | Salmonella typhi |
Type of vaccine | Conjugate |
Nucleic acid content | DNA |
Age | 6 months to 45 years |
Description of the vaccine | Purified Vi polysaccharide tetanus toxoid conjugate typhoid vaccine (Vi-TT). |
Name of the manufacturer | Cadila Healthcare Ltd |
Name of the manufacturing country | India |
Year of manufacture | 2017 |
Clinical Phase status | Approved |
Bacterial strain | Gram negative bacteria. |
Efficacy | The seroconversion rate among ZyVac-TCV recipients was 94.8%. |
Vaccine formulation | Liquid |
Dosage | Two doses, second dose is given 3 years of first dose. |
Mechanism of action | The tetanus toxoid acts as conjugation protein and it helps the immune system to recognize the antigens more effectively. |
Route of administration | Intramuscular |
Indications | Active immunization to prevent typhoid fever. |
Export | Marketing authorization only in India |
Approval | Licensed in India |
Adjuvant | NA |
Repurposing | NA |
Side effects of vaccine | Mild to moderate fever, injection site pain and swelling, irritability, headache, lose motions, vomiting. |
Post vaccination | NA |
Dose type | Single dose |
Interspecies transfer | NA |
PubMed identifier | 32134011, 32725225 |
Clinical trial number | NA |
Reference | https://drbhole.com/zyvac-tcv |
Other name | NA |
Additional Links | NA
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