ID | 1070 |
Name of the vaccine | Pentacel |
Microbe | Bacteria |
Disease name | Tetanus (Lock Jaw) |
Name of bacteria | Clostridium tetani |
Type of vaccine | Inactivated |
Nucleic acid content | DNA |
Age | 6 weeks to 4 years |
Description of the vaccine | Diphtheria, Tetanus Toxoids, Acellular Pertussis Adsorbed, Inactivated Poliovirus and Haemophilus b Conjugate (Tetanus Toxoid Conjugate) (DTaP vaccine). |
Name of the manufacturer | Sanofi Pasteur Limited and Sanofi Pasteur SA
|
Name of the manufacturing country | Canada and France |
Year of manufacture | 2008 |
Clinical Phase status | Approved |
Bacterial strain | An obligate anaerobic bacillus, which is gram positive. |
Efficacy | Post-Dose 3 : Tetanus Antitoxoid % greater than or equal to 0.10 IU/mL - 99.7%.
Post-Dose 4: Tetanus Antitoxoid % greater than or equal to 0.10 IU/mL - 100.0%, % greater than or equal to 1.0 IU/mL - 92.9%. |
Vaccine formulation | Suspension for injection as a liquid vaccine. |
Dosage | The four dose immunization series administered at 2, 4, 6 and 15-18 months. |
Mechanism of action | Serum tetanus antitoxin level of greater than or equal to 0.1 IU/mL is protective. |
Route of administration | Intramuscular |
Indications | The safety and effectiveness in infants less than 6 weeks and in children 5 to 16 years have not been established. |
Export | Distributed by- Sanofi Pasteur Inc. , USA |
Approval | US FDA |
Adjuvant | Aluminium phosphate |
Repurposing | For diphtheria, tetanus, poliovirus and Haemophilus b. |
Side effects of vaccine | Fussiness, inconsolable crying, fever, tenderness and increase in arm circumference. |
Post vaccination | NA |
Dose type | Combination doses |
Interspecies transfer | NA |
PubMed identifier | NA |
Clinical trial number | NCT00804284 |
Reference | https://www.fda.gov/media/74385/download |
Other name | NA |
Additional Links | NA
|