ID | 1012 |
Name of the vaccine | Quadracel |
Microbe | Bacteria |
Disease name | Diphtheria |
Name of bacteria | Corynebacterium diphtheriae |
Type of vaccine | Inactivated |
Nucleic acid content | DNA |
Age | 4 to 6 years |
Description of the vaccine | Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed and Inactivated Poliovirus Vaccine (DTaP vaccine). |
Name of the manufacturer | Sanofi Pasteur Limited |
Name of the manufacturing country | Canada |
Year of manufacture | 2015 |
Clinical Phase status | Approved |
Bacterial strain | Gram-positive bacillus. |
Efficacy | 100% of immunized children achieved serum diphtheria and tetanus antitoxin levels of at least 0.01 IU/mL .
99 and 100% achieved serum antitoxin levels of at least 0.1 IU/mL.
After booster dose, 100% achieved serum antitoxin levels of at least 0.1 IU/mL. |
Vaccine formulation | Suspension for injection |
Dosage | Single dose (0.5 mL) vials. |
Mechanism of action | Serum diphtheria antitoxin level of 1 IU/ml provides long-term protection. |
Route of administration | Intramuscular |
Indications | If Quadracel is administered to immunocompromised persons the expected immune response may not be obtained. |
Export | Distributed by - Sanofi Pasteur Inc., USA |
Approval | US FDA |
Adjuvant | Aluminium phosphate |
Repurposing | Could be used for pertussis, tetanus and poliovirus. |
Side effects of vaccine | Pain, increase in arm circumference, erythema, swelling, myalgia, malaise, and headache. |
Post vaccination | NA |
Dose type | Single dose |
Interspecies transfer | NA |
PubMed identifier | NA |
Clinical trial number | NA |
Reference | https://www.fda.gov/media/91640/download |
Other name | NA |
Additional Links | https://products.sanofi.ca/en/quadracel.pdf
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