Primary information |
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AHTPDB ID | 3743 |
PMID | 24262574 |
YEAR | 2014 |
SEQUENCE | EGEPR |
LENGTH | 5 |
MOL WT | 587.3 |
IC50 | 728.2 ± 6.6 μM |
pIC50 | ND |
SOURCE | Fungi (Agaricus bisporus) |
TESTED ON | ND |
PURIFICATION | SEC, RP-HPLC, LC-MS/MS |
ASSAY | ACE inhibitory assay kit (ACE kit-WST, Dojindo Lab |
BITTERNESS | ND |
ISOELECTRIC POINT | 4.53 |
SYSTOLIC BP DECREASE | ND |
Secondary information |
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Properties | Physico-Chemical details |
STRUCTURE | |
DSSP states | CCCCC |
SMILES | N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)O |
External Links to PDB, Swiss-Prot and IEDB |
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PDB exact | PDB partial | SP exact | SP partial | IEDB exact | IEDB partial |
NA |
NA |
NA |
NA from TO |
NA |
NA |
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Reference Informaiton |
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ARTICLE/REFERENCE | Novel angiotensin I-converting enzyme inhibitory peptides derived from edible mushroom Agaricus bisporus (J.E. Lange) Imbach identified by LC–MS/MS |
AUTHORS/PRIMARY REFERENCE | Ching Ching Lau, Noorlidah Abdullah, Adawiyah Suriza Shuib, Norhaniza Aminudin |
JOURNAL/EXTRA LINKS | Food Chemistry, 148, 1 April 2014, 396–401 |