| Primary information |
|---|
| AHTPDB ID | 2973 |
| PMID | 23638059 |
| YEAR | 2013 |
| SEQUENCE | VPPIPP |
| LENGTH | 6 |
| MOL WT | 618.77 |
| IC50 | 34.71 % |
| pIC50 | ND |
| SOURCE | Chemically synthesized |
| TESTED ON | SHR |
| PURIFICATION | ND |
| ASSAY | Nakamura et al. (1995), Wu and Ding et al |
| BITTERNESS | ND |
| ISOELECTRIC POINT | 5.49 |
| SYSTOLIC BP DECREASE | 21 % |
| Secondary information |
|---|
| Properties | Physico-Chemical details |
| STRUCTURE | |
| DSSP states | CCSSCC |
| SMILES | N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)O |
| External Links to PDB, Swiss-Prot and IEDB |
|---|
| PDB exact | PDB partial | SP exact | SP partial | IEDB exact | IEDB partial |
| NA |
NA |
NA |
NA
from
TO
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NA |
NA |
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| Reference Informaiton |
|---|
| ARTICLE/REFERENCE | VPPIPP and IPPVPP: two hexapeptides innovated to exert antihypertensive activity. |
| AUTHORS/PRIMARY REFERENCE | Ding F1, Qian B, Zhao X, Shen S, Deng Y, Wang D, Zhang F, Sui Z, Jing P. |
| JOURNAL/EXTRA LINKS | PLoS One. 2013 Apr 30;8(4):e62384. |