It is important to know which drugs have similar level of effectiveness for a given cell line or tissue type. This page allows the user to cluster drugs screened against selected cell line and group on the basis of IC50 or relative drug sensitivity. User can either choose the tissue type, all cell lines or can select the cell lines with mutated drug targets. The second column gives the number of drugs screened against the particular cell line as it is equal to or greater than reference IC50 (lowest of all IC50s). Subsequent columns, up to eighth, give grouping based on IC50 value equal or greater than 3, 5, 25, 100 and 250 times of reference IC50. The columns from nine to sixteen show the group of drugs with absolute value of IC50 lying in different ranges (R1, R2, R3, R4, R5, R6, R7 and R8). The drugs in groups with higher value are important for resistance-mechanism related studies. For more information, please click |
