Distribution of Potential siRNA Suppressors

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This page provides list of potential siRNA that may suppress mRNA sequence of Ebola, predicted using software desiRm. Tables include Exclusive Ebola 19mers which are absent in Human coding regions and also most effective siRNAs as per predicted by desiRm software.

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Gene (variants)Gene	Number of siRNA suppressors in different species
	SUDV	RESTV	EBOV	TAFV	BDBV
NP	436	523	480	541	487
VP35	226	232	183	218	224
VP40	205	239	151	206	235
GP (Spike)	366	392	385	416	388
GP (Small Secreted)	173	194	209	230	195
GP (Second Secreted)	-	-	145	184	157
VP30	232	234	226	217	237
VP24	195	164	198	194	163
L	1859	1995	2021	1901	1869

Detailed description is in expandable tables as follows for 5 species.

SPECIES 1 - NC_006432.1 - Sudan (SUDV) -

Gene Length Excl Above 0.8 NP 2217 1282 436 VP35 990 560 226 VP40 981 554 205 GP (Spike) 2031 1072 366 GP (Small secreted) 1119 510 173 VP30 867 544 232 VP24 756 492 195 L 6633 4654 1859

SPECIES 2 - NC_004161.1 - Reston (RESTV) +

Gene Length Excl Above 0.8 NP 2220 1326 523 VP35 990 597 232 VP40 996 633 239 GP (Spike) 2034 1191 392 GP (Small secreted) 1104 587 194 VP30 864 598 234 VP24 756 485 164 L 6639 4713 1995

SPECIES 3 - NC_002549.1 - Zaire (EBOV) +

Gene Length Excl Above 0.8 NP 2220 1366 480 VP35 1023 592 183 VP40 981 508 151 GP (Spike) 2031 1179 385 GP (Small secreted) 1095 568 209 GP (Second secreted) 894 412 145 VP30 867 556 226 VP24 756 464 198 L 6639 4917 2021

SPECIES 4 - NC_014372.1 - Tai Forest (TAFV) +

Gene Length Excl Above 0.8 NP 2220 1333 541 VP35 1026 644 218 VP40 981 553 206 GP (Spike) 2031 1324 416 GP (Soluble secreted) 1098 713 230 GP (Second secreted) 909 567 184 VP30 870 517 217 VP24 756 460 194 L 6633 4590 1901

SPECIES 5 NC_014373.1 Bundibugyo (BDBV)+

Gene Length Excl Above 0.8 NP 2220 1354 487 VP35 1026 620 224 VP40 981 639 235 GP (Spike) 2031 1333 388 GP (Soluble secreted) 1122 661 195 GP (Second secreted) 909 538 157 VP30 870 564 237 VP24 756 435 163 L 6633 4648 1869