EbolaVCR: Computational resources for designing drugs and vaccines against EBOLA virus

Welcome to Home page of EbolaVCR

Ebola Virus Computational Resources (EbolaVCR) is the in silico resources developed to facilitate scientific community fighting against deadly virus EBOLA. This server enlists possible vaccine candidates, therapeutic siRNAs and other related resources.

Reference: Dhanda et. al. (2016) A web-based resource for designing therapeutics against Ebola Virus. Sci Rep. 6:24782.

Peptide	5717
Sequence	282
Location in protein	Reston Ebola Virus (RESTV)
Source Gene ID	gi_22789230
Source Protein ID	NP_690583.1
Source Protein Symbol	GP
Source Protein Name	spike_glycoprotein_precursor
Source strain	reston ebola
Conservation Level	0
Found in human reference proteome	0.28
Found in human 1000-genome based proteome	NO
B cell epitope	4
MHC class I allele	N
HLA allele	8
MHC class II allele	0
Interferon-gamma inducing score	NO(N)
Interleukin-4 inducing score	YES(0.32)

General Information

Home Page
Genome of ebolaviruses
Alignment of Antigens/mRNA

Subunit Vaccine Targets

Species-specific Peptides
Browse Conserved Peptides
Mapping of predicted epitopes
Potential vaccine epitopes
Antigen-wise summary
Species-wise summary

siRNA based therapeutics

Potential siRNA supressors
Target-wise siRNA
Species-wise summary

Computational Tools

Map IEDB on Ebola
Epitope in query protein
Structure of Ebola Proteins
Phylogeny

Useful Links