A database of FDA approved therapeutic peptides and proteins
ID | ThPPID | Name | Peptide Sequence | Length | Functional Classification | Disease | Brand | Company | Physical Appearance | Route of Administartion | Category | Target |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1049 | Th1008 | Peginterferon alfa-2a | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological | Pegasys | Hoffman-La Roche Inc | Sterile, preservative-free, colorless to light yellow injectable solution | Subcutaneous Injection | Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1059 | Th1010 | Interferon alfa-n1 | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Infectious /Immunological | Wellferon | GlaxoSmithKline | Solution | Injection | Antiviral Agents, Immunologic factors, Immunosuppressiv agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1064 | Th1011 | Darbepoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Aranesp | Amgen Inc | Sterile, colorless, preservative-free solution containing polysorbate | Intravenousor Subcutaneous administration | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
1071 | Th1013 | Epoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Binocrit | Sandoz | Clear colourless solution | Subcutaneous and Intravenous infusion | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
1072 | Th1013 | Epoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Epocept | Lupin pharma | N.A. | Injection | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
1073 | Th1013 | Epoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Epofit | Intas pharma | N.A. | N.A. | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
1074 | Th1013 | Epoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Epogen | Amgen Inc. | Sterile, colorless liquid | Subcutaneous Injection | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
1075 | Th1013 | Epoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Epogin | Chugai | N.A. | Subcutaneous or by Intravenous. | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
1076 | Th1013 | Epoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Eprex | Janssen-Cilag. Ortho Biologics LLC | Solution | Subcutaneous and Intravenous infusion | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
1077 | Th1013 | Epoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Nanokine | Nanogen Pharmaceutical biotechnology, Vietnam) | Sterile, white, lyophilized powder. The reconstituted preparation with 1 ml solvent (containing 0.9% benzyl alcohol) results in a clear, colorless solution. | Injection | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
1078 | Th1013 | Epoetin alfa | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Hematological | Procrit | Ortho Biotech | Sterile, colorless liquid in an isotonic sodium chloride/sodium citrate buffered solution or a sodium chloride/sodium phosphate buffered solution | Intravenous(IV) or Subcutaneous (SC) administration. | Anti-anemic Agents, Hematinics | Erythropoietin receptor |
1117 | Th1016 | Pegfilgrastim | MTPLGPASSLPQSFLLKCLE Full view | 175 | Ib | Immunological | Neulasta | Amgen Inc. | Solution | Subcutaneous injection | Immunosuppressive Agents, Anti-neutropenic agents | Granulocyte colony-stimulating factor receptor,Neutrophil elastase |
1120 | Th1017 | Sargramostim | APARSPSPSTQPWEHVNAIQ Full view | 127 | Ib | Immunological | Leucomax | Novartis | Solution | Subcutaneous and Intravenous infusion | Immunosuppressive Agents | Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,Interleukin-3 receptor subunit alpha,Cytokine receptor common subunit beta,Syndecan-2,Bone marrow proteoglycan |
1121 | Th1017 | Sargramostim | APARSPSPSTQPWEHVNAIQ Full view | 127 | Ib | Immunological | Leukine | Berlex Laboratories Inc | Sterile, preserved (1.1% benzyl alcohol), injectable solution (500 mcg/mL) and also as sterile, white, preservative free lyophilized powder (250 mcg) that requires reconstitution with 1 mL sterile water for Injection | Subcutaneous Injection (SC) or Intravenous infusion (IV) | Immunosuppressive Agents | Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,Interleukin-3 receptor subunit alpha,Cytokine receptor common subunit beta,Syndecan-2,Bone marrow proteoglycan |
1135 | Th1019 | Peginterferon alfa-2b | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological | PEG-Intron | Schering Corp | Powder | Subcutaneous injection | Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1136 | Th1019 | Peginterferon alfa-2b | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological | Unitron PEG | N.A. | Lyophilized powder | Subcutaneous injection | Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1180 | Th1023 | Anakinra | MRPSGRKSSKMQAFRIWDVN Full view | 153 | IIa | Immunological | Kineret | Amgen Inc | Sterile, clear, colorless-to-white, preservative free solution | Subcutaneous (SC) administration | Immunosuppressive Agents, Anti-rheumatic agents | Interleukin-1 receptor type 1 |
1226 | Th1030 | Interferon gamma-1b | CYCQDPYVKEAENLKKYFNA Full view | 146 | Ib | Immunological | Actimmune | InterMune Inc | Sterile, clear, colorless solution | Subcutaneous Injection | Immunosuppressive Agents | Interferon gamma receptor 1,Interferon gamma receptor 2 |
1229 | Th1031 | Interferon Alfa-2a, Recombinant | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological | Roferon A | Hoffmann-La Roche Inc | Solution | Subcutaneous Injection | N.A. | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1230 | Th1031 | Interferon Alfa-2a, Recombinant | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological | Veldona | Amarillo Biosciences | N.A. | N.A. | N.A. | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1242 | Th1033 | Oprelvekin | GPPPGPPRVSPDPRAELDST Full view | 177 | Ib | Cancer/Haemetological | Neumega | Genetics Institute Inc | Sterile, lyophilized powder | Subcutaneous injection | Coagulants and Thrombotic Agents, Anti-neoplastic agents | Interleukin-11 receptor subunit alpha |
1246 | Th1034 | Palifermin | SYDYMEGGDIRVRRLFCRTQ Full view | 140 | Ib | Cancer | Kepivance | Amgen Inc | Sterile, lyophilized powder | Intravenous infusion | Anti-Mucositis Agents | Fibroblast growth factor receptor 2,Neuropilin-1,Fibroblast growth factor receptor 1,Fibroblast growth factor receptor 4,Fibroblast growth factor receptor 3,Basement membrane-specific heparan sulfate proteoglycan core protein |
1257 | Th1036 | Aldesleukin | MAPTSSSTKKTQLQLEHLLL Full view | 134 | Ib | Cancer/Infectious | Proleukin | Chiron Corp | Sterile, white to off-white, lyophilized cake | Intravenous administration | Antineoplastic Agents, Anti-HIV agents | Interleukin-2 receptor subunit beta,Interleukin-2 receptor subunit alpha,Cytokine receptor common subunit gamma |
1341 | Th1049 | Interferon beta-1a | MSYNLLGFLQRSSNFQCQKL Full view | 166 | Ib | Cancer/Infectious/Immunological | Avonex | Biogen Inc | Lyophilized powder vial, Sterile liquid as single used prefilled syringe and also available as single use prefilled autoinjector. | Intramuscular Injection | Immunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1342 | Th1049 | Interferon beta-1a | MSYNLLGFLQRSSNFQCQKL Full view | 166 | Ib | Cancer/Infectious/Immunological | Betaferon | Bayer | Powder and solvent that are made upto make solution. | Subcutaneous Injection | Immunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1343 | Th1049 | Interferon beta-1a | MSYNLLGFLQRSSNFQCQKL Full view | 166 | Ib | Cancer/Infectious/Immunological | Betaseron | Merck | Sterile, white to off-white powder | Subcutaneous Injection | Immunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1344 | Th1049 | Interferon beta-1a | MSYNLLGFLQRSSNFQCQKL Full view | 166 | Ib | Cancer/Infectious/Immunological | Blastoferon | Sidus | N.A. | N.A. | Immunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1345 | Th1049 | Interferon beta-1a | MSYNLLGFLQRSSNFQCQKL Full view | 166 | Ib | Cancer/Infectious/Immunological | Extavia | Novartis | Sterile, white to off-white powder | Subcutaneous Injection | Immunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1346 | Th1049 | Interferon beta-1a | MSYNLLGFLQRSSNFQCQKL Full view | 166 | Ib | Cancer/Infectious/Immunological | Rebif | Merck | Sterile solution in a prefilled syringe or REBIF Rebidose autoinjector | Subcutaneous Injection | Immunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1376 | Th1057 | Interferon beta-1b | MSYNLLGFLQRSSNFQSQKL Full view | 166 | Ib | Immunological | Betaseron | Bayer | Sterile, white to off-white powder | Subcutaneous Injection | Adjuvants, Immunologic and Immunosuppressive Agents | N.A. |
1377 | Th1057 | Interferon beta-1b | MSYNLLGFLQRSSNFQSQKL Full view | 166 | Ib | Immunological | Betaferon | Bayer | Powder and solvent that are made upto make solution. | Subcutaneous Injection | Adjuvants, Immunologic and Immunosuppressive Agents | N.A. |
1378 | Th1057 | Interferon beta-1b | MSYNLLGFLQRSSNFQSQKL Full view | 166 | Ib | Immunological | Extavia | Novartis | Sterile, white to off-white powder | Subcutaneous Injection | Adjuvants, Immunologic and Immunosuppressive Agents | N.A. |
1379 | Th1058 | Interferon alfacon-1 | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological/Infectious | INFERGEN | Kadmon Pharmaceuticals, LLC. | Sterile, clear, colorless, preservative-free liquid | Subcutaneous Injection | Antiviral Agents and Immunosuppressive Agents | Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2 |
1415 | Th1069 | Pegvisomant | FPTIPLSRLFDNAMLRAHRL Full view | 191 | IIa | Hormonal | SOMAVERT | Pfizer | Sterile, white lyophilized powder | Subcutaneous Injection | Hormone Replacement Agents | B-lymphocyte antigen CD20,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamma Fc region receptor III-A,High affinity immunoglobulin gamma Fc receptor I,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c |
1451 | Th1082 | Filgrastim | MTPLGPASSLPQSFLLKCLE Full view | 175 | Ib | Immunological | N.A. | N.A. | N.A. | N.A. | Immunosuppressive Agents, Antineutropenic Agents and Hematopoietic Agents | Lutropin-choriogonadotropic hormone receptor,Follicle-stimulating hormone receptor |
1454 | Th1084 | Becaplermin | SLGSLTIAEPAMIAECKTRT Full view | 109 | Ib | Cardiac | REGRANEX | OMJ Pharmaceuticals, Inc. San German, Puerto Rico | Gel: 0.01 %; clear, colorless to straw-colored gel | External use only | Angiogenesis Inducing Agents | T-cell surface glycoprotein CD1a,Major histocompatibility complex class I-related gene protein,Integrin alpha-L,T-lymphocyte activation antigen CD86,Low affinity immunoglobulin gamma Fc region receptor II-b,T-cell surface glycoprotein CD4,Integrin beta-1,Integrin alpha-V,Integrin beta-3 |
1456 | Th1086 | Interferon Alfa-2B, Recombinant | CDLPQTHSLGSRRTLMLLAQ Full view | 165 | Ib | Immunological | INTRON® A | Merck | Powder or solution | Intramuscular, Subcutaneous, Intralesional, or Intravenous injection | Immunosuppressive Agents | Granulocyte colony-stimulating factor receptor,Neutrophil elastase, Coagulation factor X,Coagulation factor XI,Coagulation factor VII,Coagulation factor VIII,Prothrombin,Prolow-density lipoprotein receptor-related protein 1,Vitamin K-dependent gamma-carboxylase, Platelet-derived growth factor receptor beta,Platelet-derived growth factor receptor alpha,Alpha-2-macroglobulin |
1465 | Th1089 | Palivizumab | VH region: QVTLRESG< Full view | 120 | IIIa | Infectious | Synagis | MedImmune | Sterile, preservative-free liquid solution | Intramuscular injection | Antiviral Agents | N.A. |
1635 | Th1141 | Epoetin Zeta | APPRLICDSRVLERYLLEAK Full view | 166 | Ib | Cancer | Retacrit | Norbitec | solution for injection | N.A. | N.A. | Erythropoietin receptor |
1655 | Th1151 | Somatotropin Recombinant | FPTIPLSRLFDNAMLRAHRL Full view | 192 | Ib | Hormonal/Metabolic | NutropinAQ | Genentech Inc. | Sterile, white lyophilized powder intended for subcutaneous administration after reconstitution with Bacteriostatic Water | Subcutaneous administration | Hormone Replacement Agents | Growth hormone receptor, Prolactin receptor |
1656 | Th1151 | Somatotropin Recombinant | FPTIPLSRLFDNAMLRAHRL Full view | 192 | Ib | Hormonal/Metabolic | BioTropin | Bio-Technology General (Israel) Ltd. | Sterile, white, lyophilized powder | Subcutaneous administration | Hormone Replacement Agents | Growth hormone receptor, Prolactin receptor |
1657 | Th1151 | Somatotropin Recombinant | FPTIPLSRLFDNAMLRAHRL Full view | 192 | Ib | Hormonal/Metabolic | Protropin | Genentech Inc. | Sterile, white, lyophilized powder | Intramuscular or subcutaneous administration | Hormone Replacement Agents | Growth hormone receptor, Prolactin receptor |
1817 | Th1208 | Metreleptin | MVPIQKVQDDTKTLIKTIVT Full view | 147 | Ib | Adjunct therapy | Myalept | Amylin Pharmaceuticals, LLC | Lyophilized Powder for Solution | Subcutaneous | Leptin receptor | |
1849 | Th1237 | Somatropin recombinant | FPTIPLSRLFDNAMLRAHRL Full view | 191 | Ib | Hormonal Disorders | BioTropin | Biotech General | Powder and Solvent for Solution | Subcutaneous | Hormones, Hormone Substitutes, and Hormone Antagonists | Growth hormone receptor, Prolactin receptor |
1850 | Th1237 | Somatropin recombinant | FPTIPLSRLFDNAMLRAHRL Full view | 191 | Ib | Hormonal Disorders | NutropinAQ | Genentech Inc. | Sterile liquid | Subcutaneous | Hormones, Hormone Substitutes, and Hormone Antagonists | Growth hormone receptor, Prolactin receptor |