| PolysacDB ID | 2413 |
| Carbohydrate Name | Type V capsular polysaccharide (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe Name | Streptococcus Group B (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | The native type v polysaccharide contains D-glucose, D-galactose, 2-acetamido-2-deoxy-glucose and sialic acid in a molar ratio of 3:2:1:1. It consists of a repeating backbone of -->4)-α-D-Glcp-(1-->4)-α-D-Galp-(1-->4)-β-D-Glcp-(1--> with branching at 6th and 3rd positions
|
| BCSDB Structure | N/A |
| Proposed Function | N/A |
| Antigenic Nature | Whole cells |
| Carrier Name | Nil |
| Conjugate Method | Nil |
| Antibodies | Antisera |
| Antibody Type Class | N/A |
| Assay System | ELISA, Ouchterlony diffusion |
| Cross Reactivity | Antibodies against the typeV capsuled o not cross-reactw ith other GBS capsular types and appear to recognize an epitope which is not as heavily dependent on the presenceo f the terminal side chain sialic acid residues as that of the type Ia, 11, and I11 GBS polysaccharides |
| Proposed Epitope | β-D-Gal-(1-->4)-β-D-GlcNAc segmenot of the trisaccharide side chain, which is present in the core but not in the backbone polysaccharide, also contributes to the native epitope. The residues of the linear backbone and/or the glucopyranosyl side chain also form part of the antibody-binding epitope |
| IEDB Epitope | N/A |
| Proposed Utility | This antisera helped in the determination of immunodominant epitopes in Type V polysaccharide in group B Streptococcus |
| Curator ID | AA + AS |
| Date of Curation | 04-05-2011
|
| References | 2016287 |