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| PolysacDB ID | 2410 |
| Carbohydrate Name | Type 1b polysaccharide (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe Name | Streptococcus Group B (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | N/A |
| BCSDB Structure | N/A |
| Proposed Function | N/A |
| Antigenic Nature | A mixture composed of equal parts of the vaccine suspensions of strains H36B (type Tb), 18RS21 (type II), and 1073 (nontypeable) |
| Carrier Name | Nil |
| Conjugate Method | Nil |
| Antibodies | Mab SMB19 |
| Antibody Type Class | IgM |
| Assay System | ELISA, indirect immunofluorescence |
| Cross Reactivity | This Mab reacted specifically with the sialylated form of the type 1b polysaccharide. This Mab cross-reacts with some oligosaccharides in human milk and certain fetal antigens |
| Proposed Epitope | Sialyllacto-N-tetraose residues seemed to be the immunodominant epitope |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab will help in the development of appropriate vaccines against GBS that would include the possibility of inducing major cross-reactions with human glycoconjugates |
| Curator ID | AA + AS |
| Date of Curation | 02-05-2011 |
| References | 1548081 |
| PolysacDB ID | 2411 |
| Carbohydrate Name | Type 1b polysaccharide (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe Name | Streptococcus Group B (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | N/A |
| BCSDB Structure | N/A |
| Proposed Function | N/A |
| Antigenic Nature | H36B vaccine that had been treated with 2 N acetic acid at 80°C for 10 min to largely desialylate the type lb polysaccharide. |
| Carrier Name | Nil |
| Conjugate Method | Nil |
| Antibodies | Mab SIbD2 |
| Antibody Type Class | IgM |
| Assay System | ELISA, indirect immunofluorescence |
| Cross Reactivity | This Mab reacted specifically with the de-sialylated form of the type 1b polysaccharide. This Mab cross-reacts with some oligosaccharides in human milk and certain fetal antigens |
| Proposed Epitope | Lacto-N-tetraose residues seemed to be the immunodominant epitope |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab will help in the development of appropriate vaccines against GBS that would include the possibility of inducing major cross-reactions with human glycoconjugates |
| Curator ID | AA + AS |
| Date of Curation | 03-05-2011 |
| References | 1548081 |
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Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020 |