PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
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PolysacDB ID2421
Carbohydrate NameType 1 polysaccharide antigen   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
Microbe NameStreptococcus sanguis ST3 Serotype I   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe type I antigen was a polysaccharide composed of glucose, rhamnose, and N-acetylglucosamine in a molar ratio of 1.4:2.5:1.0.
BCSDB StructureN/A
Proposed FunctionThe serotype I antigen may participate in the attachment of S. sanguis to tooth surfaces
Antigenic NatureWhole cells
Carrier NameNil
Conjugate MethodNil
AntibodiesAntisera
Antibody Type ClassN/A
Assay SystemQuantitative precipitin inhibition tests, Immunodiffusion and immunoelectrophoresis
Cross ReactivityN/A
Proposed Epitopeα-glucosidic linkage is the immunodeterminant of the type I antigen
IEDB EpitopeN/A
Proposed UtilityThis antisera helped in determining the immunodominant region in the Type 1 polysaccharide
Curator IDAA + AS
Date of Curation07-05-2011
ReferencesPMC347986

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