PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
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PolysacDB ID2464
Carbohydrate NameSurface polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
Microbe NameEubacterium saburreum strain T18   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe purified antigen was a homopolysaccharide composed of D-glycero-D-galacto-heptose (Hep.) residues. The structure of the repeating unit in the polysaccharide was: -[-6)-[α Hep.furanosyl-(1-->4)]-β-Hep.pyranosyl- (1-->6)-[α-Hep.furanosyl-(1-->2), α-Hep.furanosyl-(1-->4)]-β- Hep.pyranosyl-(1-)4-->6)-β-Hep.pyranosyl-(1-->. No heptose residues were acetylated
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureWhole cells
Carrier NameNil
Conjugate MethodNil
AntibodiesAntisera
Antibody Type ClassN/A
Assay SystemImmunodiffusion tests
Cross ReactivityN/A
Proposed EpitopeThe immunodeterminant of the antigenic polysaccharide was D-glycero-D-galacto-heptofuranosyl residues as branched nonreducing terminals
IEDB EpitopeN/A
Proposed UtilityN/A
Curator IDAA + AS
Date of Curation25-05-2011
References1408355

Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020