PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
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PolysacDB ID2386
Carbohydrate NameStreptococcal polysaccharide antigen eI   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
Microbe NameStreptococcus mutans strain MT703 serotype e   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe major fraction (eI) was identified as a polysaccharide composed of 37% glucose, 56% rhamnose, 5% protein, and 0.3% phosphorus, whereas the minor fraction (eII) contained 66% protein in addition to 10% glucose and 17% rhamnose
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureWhole cells
Carrier NameNil
Conjugate MethodNil
AntibodiesAntisera
Antibody Type ClassN/A
Assay SystemQuantitative precipitin test and immunodiffusion and/or immunoelectrophoresis
Cross ReactivityThis antisera cross-reacted with type E
Proposed EpitopeMethyl-β-D-glucopyranoside residues seemed to be the predominant epitope. A β-linked glucose-glucose dimer is the predominant antigenic determinant of the e specificity
IEDB EpitopeN/A
Proposed UtilityThis antisera may help in elucidating the antigenic specificity of E and e antigens on the surface of streptococcus mutans
Curator IDAA + AS
Date of Curation25-04-2011
ReferencesPMC420845

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PolysacDB ID2387
Carbohydrate NameStreptococcal polysaccharide antigen eI   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
Microbe NameStreptococcus mutans strain K129 serotype E   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureWhole cells
Carrier NameNil
Conjugate MethodNil
AntibodiesAntisera
Antibody Type ClassN/A
Assay SystemQuantitative precipitin test and immunodiffusion and/or immunoelectrophoresis
Cross ReactivityThis antisera was specific to E1
Proposed EpitopeMethyl-β-D-glucopyranoside residues seemed to be the predominant epitope
IEDB EpitopeN/A
Proposed UtilityThis antisera may help in elucidating the antigenic specificity of E and e antigens on the surface of streptococcus mutans
Curator IDAA + AS
Date of Curation25-04-2011
ReferencesPMC420845

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