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| PolysacDB ID | 2647 |
| Carbohydrate Name | Serotype b-specific polysaccharide antigen (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe Name | Actinobacillus actinomycetemcomitans Y4 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | Serotype b-specific antigen of A. actinomycetemcomitans is a capsular polysaccharide-like antigen consisting of a disaccharide repeating unit, 33)-a-D-fucopyranosyl-(132)-b-L-rhamnopyranosyl-(1- |
| BCSDB Structure | N/A |
| Proposed Function | SPA of A. actinomycetemcomitans plays an important role in the resistance to phagocytosis and killing by human PMNs. |
| Antigenic Nature | Whole cells |
| Carrier Name | N/A |
| Conjugate Method | N/A |
| Antibodies | IgG1 |
| Antibody Type Class | Mab S2 |
| Assay System | Chemiluminescence (CL) assay, immunoblotting and phagocytic killing assay |
| Cross Reactivity | N/A |
| Proposed Epitope | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab enhanced CL responses of human PMNs to the organism and killing of the organism by human PMNs |
| Curator ID | AA + AS |
| Date of Curation | 21-01-2012 |
| References | PMC173659 |
| PolysacDB ID | 2648 |
| Carbohydrate Name | Serotype b-specific polysaccharide antigen (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe Name | Actinobacillus actinomycetemcomitans Y4 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | Serotype b-specific antigen of A. actinomycetemcomitans is a capsular polysaccharide-like antigen consisting of a disaccharide repeating unit, 33)-a-D-fucopyranosyl-(132)-b-L-rhamnopyranosyl-(1- |
| BCSDB Structure | N/A |
| Proposed Function | SPA of A. actinomycetemcomitans plays an important role in the resistance to phagocytosis and killing by human PMNs. |
| Antigenic Nature | Whole cells |
| Carrier Name | N/A |
| Conjugate Method | N/A |
| Antibodies | IgG2a |
| Antibody Type Class | Mab S4 |
| Assay System | Chemiluminescence (CL) assay, immunoblotting and phagocytic killing assay |
| Cross Reactivity | N/A |
| Proposed Epitope | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab enhanced CL responses of human PMNs to the organism and killing of the organism by human PMNs |
| Curator ID | AA + AS |
| Date of Curation | 21-01-2012 |
| References | PMC173659 |
| PolysacDB ID | 2649 |
| Carbohydrate Name | Serotype b-specific polysaccharide antigen (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe Name | Actinobacillus actinomycetemcomitans Y4 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | Serotype b-specific antigen of A. actinomycetemcomitans is a capsular polysaccharide-like antigen consisting of a disaccharide repeating unit, 33)-a-D-fucopyranosyl-(132)-b-L-rhamnopyranosyl-(1- |
| BCSDB Structure | N/A |
| Proposed Function | SPA of A. actinomycetemcomitans plays an important role in the resistance to phagocytosis and killing by human PMNs. |
| Antigenic Nature | Whole cells |
| Carrier Name | N/A |
| Conjugate Method | N/A |
| Antibodies | IgG3 |
| Antibody Type Class | Mab S5 |
| Assay System | Chemiluminescence (CL) assay, immunoblotting and phagocytic killing assay |
| Cross Reactivity | N/A |
| Proposed Epitope | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab enhanced CL responses of human PMNs to the organism and killing of the organism by human PMNs |
| Curator ID | AA + AS |
| Date of Curation | 25-01-2012 |
| References | PMC173659 |
| PolysacDB ID | 2650 |
| Carbohydrate Name | Serotype b-specific polysaccharide antigen (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe Name | Actinobacillus actinomycetemcomitans Y4 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | Serotype b-specific antigen of A. actinomycetemcomitans is a capsular polysaccharide-like antigen consisting of a disaccharide repeating unit, 33)-a-D-fucopyranosyl-(132)-b-L-rhamnopyranosyl-(1- |
| BCSDB Structure | N/A |
| Proposed Function | SPA of A. actinomycetemcomitans plays an important role in the resistance to phagocytosis and killing by human PMNs. |
| Antigenic Nature | Whole cells |
| Carrier Name | N/A |
| Conjugate Method | N/A |
| Antibodies | IgG3 |
| Antibody Type Class | Mab S8 |
| Assay System | Chemiluminescence (CL) assay, immunoblotting and phagocytic killing assay |
| Cross Reactivity | N/A |
| Proposed Epitope | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab enhanced CL responses of human PMNs to the organism and killing of the organism by human PMNs |
| Curator ID | AA + AS |
| Date of Curation | 25-01-2012 |
| References | PMC173659 |
| PolysacDB ID | 2651 |
| Carbohydrate Name | Serotype b-specific polysaccharide antigen (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe Name | Actinobacillus actinomycetemcomitans Y4 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | Serotype b-specific antigen of A. actinomycetemcomitans is a capsular polysaccharide-like antigen consisting of a disaccharide repeating unit, 33)-a-D-fucopyranosyl-(132)-b-L-rhamnopyranosyl-(1- |
| BCSDB Structure | N/A |
| Proposed Function | SPA of A. actinomycetemcomitans plays an important role in the resistance to phagocytosis and killing by human PMNs. |
| Antigenic Nature | Whole cells |
| Carrier Name | N/A |
| Conjugate Method | N/A |
| Antibodies | IgM |
| Antibody Type Class | Mab S9 |
| Assay System | Chemiluminescence (CL) assay, immunoblotting and phagocytic killing assay |
| Cross Reactivity | N/A |
| Proposed Epitope | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab did not enhance CL responses of human PMNs to the organism and did not promote killing of the organism by human PMNs |
| Curator ID | AA + AS |
| Date of Curation | 25-01-2012 |
| References | PMC173659 |
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Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020 |