| PolysacDB ID | 2496 |
| Carbohydrate Name | O-polysaccharide [Terminal disaccharide] (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe Name | Vibrio cholerae O1 LPS serotype Inaba (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | It is a linear unbranched homopolymer of 1,6-linked-D-galactopyranosyl residues. |
| BCSDB Structure | 6642 |
| Proposed Function | V. cholerae lipopolysaccharide (LPS), a critical component of the outer membrane that is required for virulence, is a known target for immune responses following infection or immunization. Antibodies specific for V. cholerae LPS are correlated with protection against cholera |
| Antigenic Nature | Glycoconjugates |
| Carrier Name | Bovine serum albumin |
| Conjugate Method | The purified carbohydrates were subjected to aminolysis to afford ethylenediamine derivatives, which were treated with squaric acid diethyl ester. The squaric acid monoesters, thus obtained, were treated with BSA to give neoglycoconjugates |
| Antibodies | Antisera |
| Antibody Type Class | IgM and IgG1 |
| Assay System | ELISA |
| Cross Reactivity | This antisera cross-reacted with V. cholerae Ogawa and Inaba LPS |
| Proposed Epitope | N/A |
| IEDB Epitope | 76775 |
| Proposed Utility | This antisera was neither vibriocidal nor protective in the infant mouse cholera model |
| Curator ID | AA + AS |
| Date of Curation | 05-06-2011
|
| References | PMC427411 |