PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
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PolysacDB ID1326
Carbohydrate NameGlycan fraction of a surface mannoprotein   (Drugpedia)
Carbohydrate ClassGlycoprotein
Microbe NameCandida albicans B311   (NCBI Taxonomy)   (Drugpedia)
Basic StructureN/A
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureWhole cells
Carrier NameNil
Conjugate MethodNil
AntibodiesMab 4E6
Antibody Type ClassIgM
Assay SystemELISA, immunofluorescence, crossed immunoelectrophoresis
Cross ReactivityThis antibody cross-reacted with 5 strains of Candida albicans and also cross-reacted with Candida tropicalis and Candida stellatoidia but did not cross-react with T. glabrata and S. cerevisiae
Proposed EpitopeN/A
IEDB EpitopeN/A
Proposed UtilityThis Mab can be used to isolate surface components and determine the chemical structures that are responsible for the immunological differences. This Mab would facilitate the development of serological assays
Curator IDAA + AS
Date of Curation13-06-2010
ReferencesPMC259333

Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020