|
|
|
|
Home | Search | Advance Search | Browse | Online Submission | Documentation & FAQ | Team | Contact us |
|
| PolysacDB ID | 1450 |
| Carbohydrate Name | FVP2 polysaccharide (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe Name | Flammulina velutipes (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | Consists of an α-(1-->4)-D-glucan, branching with a single α-D-glucan at the C-6 position to every seven residues along the main chain |
| BCSDB Structure | N/A |
| Proposed Function | FVP2 can enhance the livability of primary culture of mouse hepatocytes in vitro and decrease the release of the alanine aminotransferase (ALT) as well as apoptosis of hepatocytes after the carbon tetrachloride (CCl4) intoxication. Furthermore, FVP2 has the capability of suppressing the growth of hepatoma 22 cells and sarcoma 180 cells (S180), extending the survival time of L615 leukemia mice, and promoting the lymphocyte transformation rate, natural killer cell activity, and the interleukin-2 production index in normal and tumor-bearing (S180) mice |
| Antigenic Nature | Glycoconjugates |
| Carrier Name | Bovine serum albumin |
| Conjugate Method | The FVP2 polysaccharide was conjugated to BSA using 1-cyano-4-dimethyl-aminopyridinium tetrafluoroborate (CDAP) treatment |
| Antibodies | Mab B11D |
| Antibody Type Class | IgM |
| Assay System | Indirect ELISA, Double Immunodiffusion |
| Cross Reactivity | N/A |
| Proposed Epitope | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab provides a potentially useful tool for further study in the development of a novel and efficient immunoassay to detect FVP2 in biological specimens |
| Curator ID | AA + AS |
| Date of Curation | 14-07-2010 |
| References | 19108616 |
| PolysacDB ID | 1451 |
| Carbohydrate Name | FVP2 polysaccharide (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe Name | Flammulina velutipes (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | Consists of an α-(1-->4)-D-glucan, branching with a single α-D-glucan at the C-6 position to every seven residues along the main chain |
| BCSDB Structure | N/A |
| Proposed Function | FVP2 can enhance the livability of primary culture of mouse hepatocytes in vitro and decrease the release of the alanine aminotransferase (ALT) as well as apoptosis of hepatocytes after the carbon tetrachloride (CCl4) intoxication. Furthermore, FVP2 has the capability of suppressing the growth of hepatoma 22 cells and sarcoma 180 cells (S180), extending the survival time of L615 leukemia mice, and promoting the lymphocyte transformation rate, natural killer cell activity, and the interleukin-2 production index in normal and tumor-bearing (S180) mice |
| Antigenic Nature | Glycoconjugates |
| Carrier Name | Bovine serum albumin |
| Conjugate Method | The FVP2 polysaccharide was conjugated to BSA using 1-cyano-4-dimethyl-aminopyridinium tetrafluoroborate (CDAP) treatment |
| Antibodies | Mab C8G |
| Antibody Type Class | IgM |
| Assay System | Indirect ELISA, Double Immunodiffusion |
| Cross Reactivity | N/A |
| Proposed Epitope | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab provides a potentially useful tool for further study in the development of a novel and efficient immunoassay to detect FVP2 in biological specimens |
| Curator ID | AA + AS |
| Date of Curation | 14-07-2010 |
| References | 19108616 |
| PolysacDB ID | 1452 |
| Carbohydrate Name | FVP2 polysaccharide (Drugpedia) |
| Carbohydrate Class | Capsular polysaccharide |
| Microbe Name | Flammulina velutipes (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | Consists of an α-(1-->4)-D-glucan, branching with a single α-D-glucan at the C-6 position to every seven residues along the main chain |
| BCSDB Structure | N/A |
| Proposed Function | FVP2 can enhance the livability of primary culture of mouse hepatocytes in vitro and decrease the release of the alanine aminotransferase (ALT) as well as apoptosis of hepatocytes after the carbon tetrachloride (CCl4) intoxication. Furthermore, FVP2 has the capability of suppressing the growth of hepatoma 22 cells and sarcoma 180 cells (S180), extending the survival time of L615 leukemia mice, and promoting the lymphocyte transformation rate, natural killer cell activity, and the interleukin-2 production index in normal and tumor-bearing (S180) mice |
| Antigenic Nature | Glycoconjugates |
| Carrier Name | Bovine serum albumin |
| Conjugate Method | The FVP2 polysaccharide was conjugated to BSA using 1-cyano-4-dimethyl-aminopyridinium tetrafluoroborate (CDAP) treatment |
| Antibodies | Mab I6D |
| Antibody Type Class | IgM |
| Assay System | Indirect ELISA, Double Immunodiffusion |
| Cross Reactivity | N/A |
| Proposed Epitope | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab provides a potentially useful tool for further study in the development of a novel and efficient immunoassay to detect FVP2 in biological specimens |
| Curator ID | AA + AS |
| Date of Curation | 21-07-2010 |
| References | 19108616 |
|
Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020 |