PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
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PolysacDB ID1896
Carbohydrate NameBand 1 glycolipid antigen   (Drugpedia)
Carbohydrate ClassGlycolipid
Microbe NameParacoccidiodes brasiliensis   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe structure of glycolipid antigen is Galfβ1->6(Manpα1-->3)Manpβ1-->2Ins
BCSDB StructureN/A
Proposed FunctionN/A
Antigenic NatureWhole cells
Carrier NameNil
Conjugate MethodNil
AntibodiesMab MEST1
Antibody Type ClassIgG3
Assay SystemHigh performance thin layer chromatography immunostaining, solid phase radioimmunoassay
Cross ReactivityThis Mab cross-reacted with promastigotes of Leishmania major and epimastigotes of Trypanosoma cruzi
Proposed EpitopeTerminal residue of β-D-galactofuranose of Band 1 seems to be a part of the epitope
IEDB Epitope76842
Proposed UtilityMAb MEST-1 can be a valuable tool in studies of biological role of galactofuranose residues
Curator IDAA + AS
Date of Curation24-11-2010
References9184826

Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020