PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID2421
Carbohydrate NameType 1 polysaccharide antigen   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeStreptococcus sanguis ST3 Serotype I   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe type I antigen was a polysaccharide composed of glucose, rhamnose, and N-acetylglucosamine in a molar ratio of 1.4:2.5:1.0.
BCSDB StructureN/A
Proposed functionsThe serotype I antigen may participate in the attachment of S. sanguis to tooth surfaces
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesAntisera
Antibody type and classN/A
Assay SystemQuantitative precipitin inhibition tests, Immunodiffusion and immunoelectrophoresis
Cross-reactivityN/A
Proposed epitopesα-glucosidic linkage is the immunodeterminant of the type I antigen
IEDB EpitopeN/A
Proposed UtilityThis antisera helped in determining the immunodominant region in the Type 1 polysaccharide
Curator IDAA + AS
Date of Curation07-05-2011
ReferencesPMC347986


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