PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID2386
Carbohydrate NameStreptococcal polysaccharide antigen eI   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobeStreptococcus mutans strain MT703 serotype e   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe major fraction (eI) was identified as a polysaccharide composed of 37% glucose, 56% rhamnose, 5% protein, and 0.3% phosphorus, whereas the minor fraction (eII) contained 66% protein in addition to 10% glucose and 17% rhamnose
BCSDB StructureN/A
Proposed functionsN/A
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesAntisera
Antibody type and classN/A
Assay SystemQuantitative precipitin test and immunodiffusion and/or immunoelectrophoresis
Cross-reactivityThis antisera cross-reacted with type E
Proposed epitopesMethyl-β-D-glucopyranoside residues seemed to be the predominant epitope. A β-linked glucose-glucose dimer is the predominant antigenic determinant of the e specificity
IEDB EpitopeN/A
Proposed UtilityThis antisera may help in elucidating the antigenic specificity of E and e antigens on the surface of streptococcus mutans
Curator IDAA + AS
Date of Curation25-04-2011
ReferencesPMC420845


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