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| PolysacDB ID | 2405 |
| Carbohydrate Name | Cell wall antigen (SA I/II) (Drugpedia) |
| Carbohydrate Class | Glycoprotein |
| Microbe | Streptococcus mutans serotype c (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | N/A |
| BCSDB Structure | N/A |
| Proposed functions | N/A |
| Antigenic Nature used to produce antibodies | Cell wall antigen (SA I/II) |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab Guy 1 |
| Antibody type and class | IgG2a |
| Assay System | Solid-phase radioimmunoassy, Competitive inhibition experiments |
| Cross-reactivity | This Mab was raised against specific carbohydrate epitopes on the SA and not against contaminating c polysaccharide in the SA preparation and was specific to serotype c |
| Proposed epitopes | Glucose is part of the epitopes of SA recognized by this Mab |
| IEDB Epitope | N/A |
| Proposed Utility | His Mab can be used in local passive immunization to prevent colonization of S. mutans and the development of caries in monkeys and to prevent colonization of S. mutans in human subjects |
| Curator ID | AA + AS |
| Date of Curation | 01-05-2011 |
| References | 2434429 |
| PolysacDB ID | 2406 |
| Carbohydrate Name | Cell wall antigen (SA I/II) (Drugpedia) |
| Carbohydrate Class | Glycoprotein |
| Microbe | Streptococcus mutans serotype c (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | N/A |
| BCSDB Structure | N/A |
| Proposed functions | N/A |
| Antigenic Nature used to produce antibodies | Cell wall antigen (SA I/II) |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab Guy 2 |
| Antibody type and class | IgG1 |
| Assay System | Solid-phase radioimmunoassy, Competitive inhibition experiments |
| Cross-reactivity | This Mab was raised against specific carbohydrate epitopes on the SA and not against contaminating c polysaccharide in the SA preparation and was specific to serotype c |
| Proposed epitopes | Glucose is part of the epitopes of SA recognized by this Mab |
| IEDB Epitope | N/A |
| Proposed Utility | His Mab can be used in local passive immunization to prevent colonization of S. mutans and the development of caries in monkeys and to prevent colonization of S. mutans in human subjects |
| Curator ID | AA + AS |
| Date of Curation | 01-05-2011 |
| References | 2434429 |
| PolysacDB ID | 2407 |
| Carbohydrate Name | Cell wall antigen (SA I/II) (Drugpedia) |
| Carbohydrate Class | Glycoprotein |
| Microbe | Streptococcus mutans serotype c (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | N/A |
| BCSDB Structure | N/A |
| Proposed functions | N/A |
| Antigenic Nature used to produce antibodies | Cell wall antigen (SA I/II) |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab Guy 3 |
| Antibody type and class | IgG2a |
| Assay System | Solid-phase radioimmunoassy, Competitive inhibition experiments |
| Cross-reactivity | This Mab was raised against specific carbohydrate epitopes on the SA and not against contaminating c polysaccharide in the SA preparation and was specific to serotype c |
| Proposed epitopes | Glucose is part of the epitopes of SA recognized by this Mab |
| IEDB Epitope | N/A |
| Proposed Utility | His Mab can be used in local passive immunization to prevent colonization of S. mutans and the development of caries in monkeys and to prevent colonization of S. mutans in human subjects |
| Curator ID | AA + AS |
| Date of Curation | 01-05-2011 |
| References | 2434429 |
| PolysacDB ID | 2408 |
| Carbohydrate Name | Cell wall antigen (SA I/II) (Drugpedia) |
| Carbohydrate Class | Glycoprotein |
| Microbe | Streptococcus mutans serotype c (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | N/A |
| BCSDB Structure | N/A |
| Proposed functions | N/A |
| Antigenic Nature used to produce antibodies | Cell wall antigen (SA I/II) |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab Guy 5 |
| Antibody type and class | IgG1 |
| Assay System | Solid-phase radioimmunoassy, Competitive inhibition experiments |
| Cross-reactivity | This Mab was raised against specific carbohydrate epitopes on the SA and not against contaminating c polysaccharide in the SA preparation and was specific to serotype c |
| Proposed epitopes | Glucose is part of the epitopes of SA recognized by this Mab |
| IEDB Epitope | N/A |
| Proposed Utility | His Mab can be used in local passive immunization to prevent colonization of S. mutans and the development of caries in monkeys and to prevent colonization of S. mutans in human subjects |
| Curator ID | AA + AS |
| Date of Curation | 02-05-2011 |
| References | 2434429 |
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Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020 |