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| PolysacDB ID | 2393 |
| Carbohydrate Name | 125 Kda antigen (Drugpedia) |
| Carbohydrate Class | Glycoprotein |
| Microbe | Streptococcus mutans OMZ175 (serotype f) (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | N/A |
| BCSDB Structure | N/A |
| Proposed functions | N/A |
| Antigenic Nature used to produce antibodies | Cell wall extracted antigens |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab LOSM1 |
| Antibody type and class | IgM |
| Assay System | Western blotting and immunoprecipitation techniques, enzyme-linked immunosorbent assay (ELISA), and competitive ELISA |
| Cross-reactivity | Monoclonal antibody LOSM1 showed a quite identical reactivity with WEA from S. mutans serotypes f and b, reduced activity against WEA from serotypes c, e, and a, and weak binding to serotypes d and g |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | Using this monoclonal antibody, it has been demonstrated that cross-reactivity and conservation of the specific epitopes among the various S. mutans serotypes. These Mab should be useful in studying the streptococcal surface moities |
| Curator ID | AA + AS |
| Date of Curation | 29-04-2011 |
| References | PMC262021 |
| PolysacDB ID | 2394 |
| Carbohydrate Name | 125 Kda antigen (Drugpedia) |
| Carbohydrate Class | Glycoprotein |
| Microbe | Streptococcus mutans OMZ175 (serotype f) (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | N/A |
| BCSDB Structure | N/A |
| Proposed functions | N/A |
| Antigenic Nature used to produce antibodies | Cell wall extracted antigens |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab LOSM2 |
| Antibody type and class | IgM |
| Assay System | Western blotting and immunoprecipitation techniques, enzyme-linked immunosorbent assay (ELISA), and competitive ELISA |
| Cross-reactivity | Monoclonal antibody LOSM1 showed a quite identical reactivity with WEA from S. mutans serotypes f and b, reduced activity against WEA from serotypes c, e, and a, and weak binding to serotypes d and g |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | Using this monoclonal antibody, it has been demonstrated that cross-reactivity and conservation of the specific epitopes among the various S. mutans serotypes. These Mab should be useful in studying the streptococcal surface moities |
| Curator ID | AA + AS |
| Date of Curation | 29-04-2011 |
| References | PMC262021 |
| PolysacDB ID | 2395 |
| Carbohydrate Name | 125 Kda antigen (Drugpedia) |
| Carbohydrate Class | Glycoprotein |
| Microbe | Streptococcus mutans OMZ175 (serotype f) (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | N/A |
| BCSDB Structure | N/A |
| Proposed functions | N/A |
| Antigenic Nature used to produce antibodies | Cell wall extracted antigens |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab LOSM3 |
| Antibody type and class | IgM |
| Assay System | Western blotting and immunoprecipitation techniques, enzyme-linked immunosorbent assay (ELISA), and competitive ELISA |
| Cross-reactivity | Monoclonal antibody LOSM1 showed a quite identical reactivity with WEA from S. mutans serotypes f and b, reduced activity against WEA from serotypes c, e, and a, and weak binding to serotypes d and g |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | Using this monoclonal antibody, it has been demonstrated that cross-reactivity and conservation of the specific epitopes among the various S. mutans serotypes. These Mab should be useful in studying the streptococcal surface moities |
| Curator ID | AA + AS |
| Date of Curation | 29-04-2011 |
| References | PMC262021 |
| PolysacDB ID | 2396 |
| Carbohydrate Name | 125 Kda antigen (Drugpedia) |
| Carbohydrate Class | Glycoprotein |
| Microbe | Streptococcus mutans OMZ175 (serotype f) (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | N/A |
| BCSDB Structure | N/A |
| Proposed functions | N/A |
| Antigenic Nature used to produce antibodies | Cell wall extracted antigens |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab LOSM4 |
| Antibody type and class | IgM |
| Assay System | Western blotting and immunoprecipitation techniques, enzyme-linked immunosorbent assay (ELISA), and competitive ELISA |
| Cross-reactivity | LOSM4 reacted strongly to WEA from serotypes b and d, to a lesser extent to serotypes c, e, and a, and weakly with serotype g |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | Using this monoclonal antibody, it has been demonstrated that cross-reactivity and conservation of the specific epitopes among the various S. mutans serotypes. These Mab should be useful in studying the streptococcal surface moities |
| Curator ID | AA + AS |
| Date of Curation | 29-04-2011 |
| References | PMC262021 |
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Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020 |