PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID2353
Carbohydrate NameLipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeSinorhizobium meliloti strain RM41   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThere are two forms of LPS: rough LPS (R-LPS), which consists of a lipid A membrane anchor and conserved core oligosaccharides, and smooth LPS (S-LPS), which includes the O-antigen (or O-polysaccharide)
BCSDB StructureN/A
Proposed functionsLPS is an important surface antigen
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesAntisera
Antibody type and classN/A
Assay SystemELISA and immunoblotting
Cross-reactivityThis antisera was specific to the homologous immunizing strain
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThe antisera generated may help in understanding the prevalence of specific LPS sub-structures among various sub-species
Curator IDAA + AS
Date of Curation13-04-2011
References10543844


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