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| PolysacDB ID | 2449 |
| Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Shigella flexneri serotype X (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The O-antigen part consists of the following residues : -3)-α-D-GlcpNAc-(1-->3)-β-L-Rhap [branched to α-D-Glcp-(1-->2)] -(1-->2)-α-L-Rhap-(1-->2)-β-L-Rhap-(1- |
| BCSDB Structure | 122449 |
| Proposed functions | LPS plays an important virulence role based on its antiphagocytic and endotoxic properties |
| Antigenic Nature used to produce antibodies | Phenol killed cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab X-1 |
| Antibody type and class | IgG2a |
| Assay System | ELISA, immunodiffusion |
| Cross-reactivity | This Mab cross-reacted with 3a and 5b LPS |
| Proposed epitopes | This Mab reacted with alkali-treated LPS |
| IEDB Epitope | 76661 |
| Proposed Utility | This Mab can be used for antigenic characterization of Shigella LPS |
| Curator ID | AA + AS |
| Date of Curation | 18-05-2011 |
| References | 3531329 |
| PolysacDB ID | 2450 |
| Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Shigella flexneri serotype X (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The O-antigen part consists of the following residues : -3)-α-D-GlcpNAc-(1-->3)-β-L-Rhap [branched to α-D-Glcp-(1-->2)] -(1-->2)-α-L-Rhap-(1-->2)-β-L-Rhap-(1- |
| BCSDB Structure | 122449 |
| Proposed functions | LPS plays an important virulence role based on its antiphagocytic and endotoxic properties |
| Antigenic Nature used to produce antibodies | Phenol killed cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab X-4 |
| Antibody type and class | IgG3 |
| Assay System | ELISA, immunodiffusion |
| Cross-reactivity | This Mab cross-reacted with 3a LPS |
| Proposed epitopes | This Mab reacted with alkali-treated LPS and O-antigen |
| IEDB Epitope | 76661 |
| Proposed Utility | This Mab can be used for antigenic characterization of Shigella LPS |
| Curator ID | AA + AS |
| Date of Curation | 18-05-2011 |
| References | 3531329 |
| PolysacDB ID | 2451 |
| Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Shigella flexneri serotype X (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The O-antigen part consists of the following residues : -3)-α-D-GlcpNAc-(1-->3)-β-L-Rhap [branched to α-D-Glcp-(1-->2)] -(1-->2)-α-L-Rhap-(1-->2)-β-L-Rhap-(1- |
| BCSDB Structure | 122449 |
| Proposed functions | LPS plays an important virulence role based on its antiphagocytic and endotoxic properties |
| Antigenic Nature used to produce antibodies | Phenol killed cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab X-5 |
| Antibody type and class | IgM |
| Assay System | ELISA, immunodiffusion |
| Cross-reactivity | This Mab cross-reacted with 3a and 5b LPS |
| Proposed epitopes | This Mab reacted with alkali-treated LPS and O-antigen |
| IEDB Epitope | 76661 |
| Proposed Utility | This Mab can be used for antigenic characterization of Shigella LPS |
| Curator ID | AA + AS |
| Date of Curation | 19-05-2011 |
| References | 3531329 |
| PolysacDB ID | 2452 |
| Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Shigella flexneri serotype X (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The O-antigen part consists of the following residues : -3)-α-D-GlcpNAc-(1-->3)-β-L-Rhap [branched to α-D-Glcp-(1-->2)] -(1-->2)-α-L-Rhap-(1-->2)-β-L-Rhap-(1- |
| BCSDB Structure | 122449 |
| Proposed functions | LPS plays an important virulence role based on its antiphagocytic and endotoxic properties |
| Antigenic Nature used to produce antibodies | Phenol killed cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab X-9 |
| Antibody type and class | IgM |
| Assay System | ELISA, immunodiffusion |
| Cross-reactivity | This Mab cross-reacted with 3a LPS |
| Proposed epitopes | N/A |
| IEDB Epitope | 76661 |
| Proposed Utility | This Mab can be used for antigenic characterization of Shigella LPS |
| Curator ID | AA + AS |
| Date of Curation | 20-05-2011 |
| References | 3531329 |
| PolysacDB ID | 2453 |
| Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Shigella flexneri serotype X (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The O-antigen part consists of the following residues : -3)-α-D-GlcpNAc-(1-->3)-β-L-Rhap [branched to α-D-Glcp-(1-->2)] -(1-->2)-α-L-Rhap-(1-->2)-β-L-Rhap-(1- |
| BCSDB Structure | 122449 |
| Proposed functions | LPS plays an important virulence role based on its antiphagocytic and endotoxic properties |
| Antigenic Nature used to produce antibodies | Phenol killed cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab X-13 |
| Antibody type and class | IgM |
| Assay System | ELISA, immunodiffusion |
| Cross-reactivity | This Mab cross-reacted with 2b, 3a and 5b LPS |
| Proposed epitopes | This Mab reacted with alkali-treated LPS and O-antigen |
| IEDB Epitope | 76661 |
| Proposed Utility | This Mab can be used for antigenic characterization of Shigella LPS |
| Curator ID | AA + AS |
| Date of Curation | 21-05-2011 |
| References | 3531329 |
| PolysacDB ID | 2454 |
| Carbohydrate Name | Lipopolysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Shigella flexneri serotype X (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The O-antigen part consists of the following residues : -3)-α-D-GlcpNAc-(1-->3)-β-L-Rhap [branched to α-D-Glcp-(1-->2)] -(1-->2)-α-L-Rhap-(1-->2)-β-L-Rhap-(1- |
| BCSDB Structure | 122449 |
| Proposed functions | LPS plays an important virulence role based on its antiphagocytic and endotoxic properties |
| Antigenic Nature used to produce antibodies | Phenol killed cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab X-15 |
| Antibody type and class | IgG3 |
| Assay System | ELISA, immunodiffusion |
| Cross-reactivity | This Mab cross-reacted with 3a LPS |
| Proposed epitopes | This Mab reacted with alkali-treated LPS and O-antigen |
| IEDB Epitope | 76661 |
| Proposed Utility | This Mab can be used for antigenic characterization of Shigella LPS |
| Curator ID | AA + AS |
| Date of Curation | 21-05-2011 |
| References | 3531329 |
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Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020 |