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| PolysacDB ID | 2279 |
| Carbohydrate Name | O-polysaccharide (Drugpedia) |
| Carbohydrate Class | Lipopolysaccharide |
| Microbe | Shigella flexneri serotype 6 (NCBI Taxonomy) (Drugpedia) |
| Basic Structure | O-specific chain of Shigella flexneri 6 lipopolysaccharide was found to be composed mainly of rhamnose, N-acetylgalactosamine and O-acetyl groups. The structure of which is as follows: --[3-GlcNAc-1-->3-Rha 1-->2-Rha-1--]n,where the terminal rhamnose residue may be linked to another rhamnose residue via 1-->4 linkage. |
| BCSDB Structure | 188 |
| Proposed functions | LPS plays an important virulence role based on its antiphagocytic and endotoxic properties |
| Antigenic Nature used to produce antibodies | Whole cells |
| Carrier Name | Nil |
| Conjugation Method | Nil |
| Antibodies | Mab MASF VI-1 |
| Antibody type and class | IgG3 |
| Assay System | ELISA |
| Cross-reactivity | This Mab was specific to serotype 6 |
| Proposed epitopes | N/A |
| IEDB Epitope | N/A |
| Proposed Utility | This Mab may prove to be valuable reagents in the studies of protective immunity against Shigella bacteria |
| Curator ID | AA + AS |
| Date of Curation | 17-03-2011 |
| References | 2437036 |
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Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020 |