PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 4

Entry No. - 1   [TOP]
PolysacDB ID1918
Carbohydrate NameCapsular polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobePneumococci spp.   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe capsular polysaccharide of Pneumococcus sp. 14 consists of the following residues : -4)-β-D-Glcp-(1-->6)-β-D-GlcpNAc [branched to β-D-Galp-(1-->4)] -(1-->3)-β-D-Galp-(1-
BCSDB Structure21255
Proposed functionsN/A
Antigenic Nature used to produce antibodiesA vaccine preparation of type 6 (Danish type 6A) pneumococcal capsular polysaccharide
Carrier NameNil
Conjugation MethodNil
AntibodiesPolysera
Antibody type and classN/A
Assay SystemHemolytic plaque assay
Cross-reactivityThe antisera cross-reacted with S14, S19, or S23 capsular polysaccharides
Proposed epitopesThe antisera was proposed to be directed against a immunodominant polysaccharide PnC
IEDB EpitopeN/A
Proposed UtilityN/A
Curator IDAA + AS
Date of Curation28-11-2010
ReferencesPMC260941


Entry No. - 2   [TOP]
PolysacDB ID1919
Carbohydrate NameCapsular polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobePneumococci spp.   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe capsular polysaccharide of Pneumococcus sp. 14 consists of the following residues : -4)-β-D-Glcp-(1-->6)-β-D-GlcpNAc [branched to β-D-Galp-(1-->4)] -(1-->3)-β-D-Galp-(1-
BCSDB Structure21255
Proposed functionsN/A
Antigenic Nature used to produce antibodiesA vaccine preparation of type 14 pneumococcal capsular polysaccharide
Carrier NameNil
Conjugation MethodNil
AntibodiesPolysera
Antibody type and classN/A
Assay SystemHemolytic plaque assay
Cross-reactivityThe antisera cross-reacted with S6, S19, or S23 capsular polysaccharides
Proposed epitopesThe antisera was proposed to be directed against a immunodominant polysaccharide PnC
IEDB EpitopeN/A
Proposed UtilityN/A
Curator IDAA + AS
Date of Curation29-11-2010
ReferencesPMC260941


Entry No. - 3   [TOP]
PolysacDB ID1920
Carbohydrate NameCapsular polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobePneumococci spp.   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe capsular polysaccharide of Pneumococcus sp. 14 consists of the following residues : -4)-β-D-Glcp-(1-->6)-β-D-GlcpNAc [branched to β-D-Galp-(1-->4)] -(1-->3)-β-D-Galp-(1-
BCSDB Structure21255
Proposed functionsN/A
Antigenic Nature used to produce antibodiesA vaccine preparation of type 19 pneumococcal capsular polysaccharide
Carrier NameNil
Conjugation MethodNil
AntibodiesPolysera
Antibody type and classN/A
Assay SystemHemolytic plaque assay
Cross-reactivityThe antisera cross-reacted with S14, S6, or S23 capsular polysaccharides
Proposed epitopesThe antisera was proposed to be directed against a immunodominant polysaccharide PnC
IEDB EpitopeN/A
Proposed UtilityN/A
Curator IDAA + AS
Date of Curation29-11-2010
ReferencesPMC260941


Entry No. - 4   [TOP]
PolysacDB ID1921
Carbohydrate NameCapsular polysaccharide   (Drugpedia)
Carbohydrate ClassCapsular polysaccharide
MicrobePneumococci spp.   (NCBI Taxonomy)   (Drugpedia)
Basic StructureThe capsular polysaccharide of Pneumococcus sp. 14 consists of the following residues : -4)-β-D-Glcp-(1-->6)-β-D-GlcpNAc [branched to β-D-Galp-(1-->4)] -(1-->3)-β-D-Galp-(1-
BCSDB Structure21255
Proposed functionsN/A
Antigenic Nature used to produce antibodiesA vaccine preparation of type 23 pneumococcal capsular polysaccharide
Carrier NameNil
Conjugation MethodNil
AntibodiesPolysera
Antibody type and classN/A
Assay SystemHemolytic plaque assay
Cross-reactivityThe antisera cross-reacted with S14, S19, or S6 capsular polysaccharides
Proposed epitopesThe antisera was proposed to be directed against a immunodominant polysaccharide PnC
IEDB EpitopeN/A
Proposed UtilityN/A
Curator IDAA + AS
Date of Curation29-11-2010
ReferencesPMC260941


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