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PolysacDB ID | 1547 |
Carbohydrate Name | Lipophosphoglycan (Drugpedia) |
Carbohydrate Class | Glycolipid |
Microbe | Leishmania mexicana (NCBI Taxonomy) (Drugpedia) |
Basic Structure | LPG contains [PO4-->6Gal(β1-->4)Man(α1)] phosphosaccharide repeats linked to a conserved phosphosaccharide core and a conserved lyso alkylphosphatidylinositol residue. In contrast to L. donovani LPG, which exclusively contains the phosphodisaccharide repeats |
BCSDB Structure | 2568 |
Proposed functions | N/A |
Antigenic Nature used to produce antibodies | Concanavalin A (ConA)-binding membrane components from L. mexicana |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab L7.25 |
Antibody type and class | IgM |
Assay System | ELISA, immunoblotting |
Cross-reactivity | This Mab cross-reacted with a highly glycosylated protein - acid phosphatase |
Proposed epitopes | The epitope was proposed to consist of phosphosaccharide repeats or the sugar residues forming the cap at the non-reducing end |
IEDB Epitope | 76720 |
Proposed Utility | The epitopes recognized by this Mab have been localized in promastigotes and infected macrophages |
Curator ID | AA + AS |
Date of Curation | 03-09-2010 |
References | 1721919 |
PolysacDB ID | 1548 |
Carbohydrate Name | Lipophosphoglycan (Drugpedia) |
Carbohydrate Class | Glycolipid |
Microbe | Leishmania mexicana (NCBI Taxonomy) (Drugpedia) |
Basic Structure | LPG contains [PO4-->6Gal(β1-->4)Man(α1)] phosphosaccharide repeats linked to a conserved phosphosaccharide core and a conserved lyso alkylphosphatidylinositol residue. In contrast to L. donovani LPG, which exclusively contains the phosphodisaccharide repeats |
BCSDB Structure | 2568 |
Proposed functions | N/A |
Antigenic Nature used to produce antibodies | Con A binding proteins |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab AP3 |
Antibody type and class | IgG1 |
Assay System | ELISA, immunoblotting |
Cross-reactivity | This Mab cross-reacted with a highly glycosylated protein - acid phosphatase |
Proposed epitopes | The epitope was proposed to consist of phosphosaccharide repeats or the sugar residues forming the cap at the non-reducing end |
IEDB Epitope | 76720 |
Proposed Utility | The epitopes recognized by this Mab have been localized in promastigotes and infected macrophages |
Curator ID | AA + AS |
Date of Curation | 04-09-2010 |
References | 1721919 |
PolysacDB ID | 1549 |
Carbohydrate Name | Unknown carbohydrate (Drugpedia) |
Carbohydrate Class | Glycolipid |
Microbe | Leishmania mexicana (NCBI Taxonomy) (Drugpedia) |
Basic Structure | N/A |
BCSDB Structure | N/A |
Proposed functions | N/A |
Antigenic Nature used to produce antibodies | Con A binding proteins |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab L3.13 |
Antibody type and class | IgG1 |
Assay System | ELISA, immunoblotting |
Cross-reactivity | This Mab cross-reacted with a highly glycosylated protein - acid phosphatase |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | The epitopes recognized by this Mab have been localized in promastigotes and infected macrophages |
Curator ID | AA + AS |
Date of Curation | 04-09-2010 |
References | 1721919 |
Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020 |