PolysacDB: A comprehensive database of microbial polysaccharide antigens and their antibodies

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Citation: Aithal A, Sharma A, Joshi S, Raghava GPS, Varshney GC (2012) PolysacDB: A Database of Microbial Polysaccharide Antigens and Their Antibodies. PLoS ONE 7(4): e34613. doi:10.1371/journal.pone.0034613
Total Entries - 1

Entry No. - 1   [TOP]
PolysacDB ID1460
Carbohydrate NameLipopolysaccharide   (Drugpedia)
Carbohydrate ClassLipopolysaccharide
MicrobeHaemophilus ducreyi CCUG 4438   (NCBI Taxonomy)   (Drugpedia)
Basic StructureIt consist of an oligosaccharide core ketosidically linked via a 3-deoxy-D-manno-octulosonic acid (Kdo) residue to the lipid A region. The oligosaccharide core characteristic of these bacteria has been divided into two regions: (i) an inner core, consisting of three L-glycero-D-manno-heptose (Hep) residues and one phosphorylated Kdo residue, and (ii) an outer core, with one or more heterogeneous oligosaccharide branches containing mainly galactose (Gal) and glucose (Glc) residues
BCSDB StructureN/A
Proposed functionsLPS plays an important role in the infection process
Antigenic Nature used to produce antibodiesWhole cells
Carrier NameNil
Conjugation MethodNil
AntibodiesPolysera
Antibody type and classN/A
Assay SystemELISA and immunoblotting
Cross-reactivityThe antiserum to CCUG 4438 reacted with only its homologous strain and strain ITM 4747
Proposed epitopesN/A
IEDB EpitopeN/A
Proposed UtilityThis antisera would aid in the classification of H. ducreyi for epidemiological purposes
Curator IDAA + AS
Date of Curation23-07-2010
ReferencesPMC175445


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