|
|
Home | Search | Advance Search | Browse | Online Submission | Documentation & FAQ | Team | Contact us |
|
PolysacDB ID | 1263 |
Carbohydrate Name | Glucomannoprotein (Drugpedia) |
Carbohydrate Class | Glycoprotein |
Microbe | Candida albicans serotype A (NCBI Taxonomy) (Drugpedia) |
Basic Structure | N/A |
BCSDB Structure | N/A |
Proposed functions | N/A |
Antigenic Nature used to produce antibodies | Glucomannoprotein-rich antigenic extract (GMP) |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab AF-1 |
Antibody type and class | IgM |
Assay System | ELISA, immunofluorescence and slide agglutination tests |
Cross-reactivity | This Mab cross-reacted with C. albicans serotypes A and B, C. tropicalis, C. guilliermondii and C. viswanathii, but did not cross-react with C. krusei, C. parapsilosis, C. kefyr (pseudotropicalis) and T. Glabrata |
Proposed epitopes | The epitope was proposed to consist of mannan residues |
IEDB Epitope | N/A |
Proposed Utility | This Mab had strong agglutination properties for Candida species. This Mab helped in the identification of new polysaccharide epitopes on the cell wall of pathogenic Candida species. |
Curator ID | AA + AS |
Date of Curation | 02-05-2010 |
References | 2462051 |
PolysacDB ID | 1351 |
Carbohydrate Name | Mannan (Drugpedia) |
Carbohydrate Class | Capsular polysaccharide |
Microbe | Candida albicans serotype A (NCBI Taxonomy) (Drugpedia) |
Basic Structure | An α-linked branched homopolymer of mannose linked to protein |
BCSDB Structure | N/A |
Proposed functions | N/A |
Antigenic Nature used to produce antibodies | Heat-killed cell suspension of C. albicans M1012(serotype A) |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab CA4-2 |
Antibody type and class | IgM |
Assay System | Slide agglutination tests, immunofluorescence |
Cross-reactivity | This Mab cross-reacted with C. tropicalis, and T. glabrata strains |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | This Mab had agglutinating properties and may be useful also as reagents for revealing the immunochemical structures of specific determinants of C. albiccanis cell wall mannans |
Curator ID | AA + AS |
Date of Curation | 26-06-2010 |
References | PMC268742 |
PolysacDB ID | 1352 |
Carbohydrate Name | Mannan (Drugpedia) |
Carbohydrate Class | Capsular polysaccharide |
Microbe | Candida albicans serotype A (NCBI Taxonomy) (Drugpedia) |
Basic Structure | An α-linked branched homopolymer of mannose linked to protein |
BCSDB Structure | N/A |
Proposed functions | N/A |
Antigenic Nature used to produce antibodies | Heat-killed cell suspension of C. albicans M1012(serotype A) |
Carrier Name | Nil |
Conjugation Method | Nil |
Antibodies | Mab CA5-4 |
Antibody type and class | IgM |
Assay System | Slide agglutination tests, immunofluorescence |
Cross-reactivity | This Mab cross-reacted with C. albicans serotype B, and C. tropicalis strains |
Proposed epitopes | N/A |
IEDB Epitope | N/A |
Proposed Utility | This Mab had agglutinating properties and may be useful also as reagents for revealing the immunochemical structures of specific determinants of C. albicans cell wall mannans |
Curator ID | AA + AS |
Date of Curation | 26-06-2010 |
References | PMC268742 |
Department of Computational Biology, Indraprastha Institute of Information Technology, Sec - 39A, New Delhi, India - 110020 |